中西医结合是一门新兴的医学交叉学科,通过对中医、西医两种医学的科学思维、理论体系、诊疗技术的整合和应用,吸收中医药学和现代医药学各自的特色和优势,在中西医结合诊治肾脏病方面取得了长足的进展。 但是由于诊断治疗不规范、研究缺乏科学的设计、没有客观的评价指标和判断标准、可重复性差,研究常常达不到预期目的,结果也得不到学术界的认可。 因此,制定科学、规范、重复性好的中医症候证型量化评估方法,采用前瞻性随机对照临床试验(RCT)及“真实世界”长期随访队列的循证医学研究,客观、科学地评价中医药单独应用或联合西药应用的有效性和安全性,促进中西医结合诊治肾脏病水平的不断提高,具有重要的意义。

Integrative Chinese and western medicine is an emerging interdisciplinarity, which has made considerable progress in the diagnosis and treatment of kidney diseases through integration and application in scientific thinking, theoretical system, and medical technology of traditional Chinese and western medicine, and through absorbing their own characteristics and advantages of both Chinese and modern medicine. However, researches often fail to achieve the intended purpose with the results not getting the academic recognition due to the irregularities in diagnosis and treatment, lack of scientific study design,no objective evaluation and judgment standards, and poor reproducibility. Therefore, for the purpose of improving diagnosis and treatment of kidney diseases with integrative traditional Chinese and western medicine, it will be of important significance to develop scientific, standardized, reproducible quantitative evaluation methods for symptom and syndromes of traditional Chinese medicine, to perform prospective randomized controlled clinical trials (RCT) and the “real-world” long-term follow-up cohort studies of evidence-based medicine, and to make objective and scientific evaluations of effectiveness and safety of traditional Chinese medicine alone or in combination with western medicine.