1 |
Regeniter A, Freidank H, Dickenmann M, et al. Evaluation of proteinuria and GFR to diagnose and classify kidney disease:systematic review and proof of concept [J]. Eur J Intern Med,2009,20(6):556-561.
|
2 |
Comper WD, Hilliard LM, Nikolic-Paterson DJ, et al. Diseasedependent mechanisms of albuminuria [J]. Am J Physiol Renal Physiol,2008,295(6): F1589-F1600.
|
3 |
Baines RJ, Brunskill NJ. The molecular interactions between filtered proteins and proximal tubular cells in proteinuria [J]. Nephron Exp Nephrol,2008,110(2): e67-e71.
|
4 |
Lee D, Gleich K, Fraser SA, et al. Limited capacity of proximal tubular proteolysis in mice with proteinuria. Am J Physiol Renal Physiol,2013,304(7): F1009-F1019.
|
5 |
Theilig F, Kriz W, Jerichow T, et al. Abrogation of protein uptake through megalin-deficient proximal tubules does not safeguard against tubulointerstitial injury [J]. J Am Soc Nephrol, 2007, 18(6):1824-1834.
|
6 |
Amsellem S, Gburek J, Hamard G, et al. Cubilin is essential for albumin reabsorption in the renal proximal tubule [J]. J Am Soc Nephrol,2010,21(11):1859-1867.
|
7 |
Weyer K, Storm T, Shan J, et al. Mouse model of proximal tubule endocytic dysfunction [J]. Nephrol Dial Transplant, 2011, 26(11):3446-3451.
|
8 |
Grösbeck R. Imerslund-Grösbeck syndrome (selective vitamin B12 malabsorption with proteinuria) [J]. Orphanet J Rare Dis, 2006,1:17.
|
9 |
Storm T, Emma F, Verroust PJ, et al. A patient with cubilin deficiency [J]. N Engl J Med,2011,364(1):89-91.
|
10 |
Yang J, He Y. Expression of renal cubilin and its potential role in tubulointerstitial inflammation induced by albumin overload [J].Front Med China,2008,2(1):25-34.
|
11 |
Liu J, Li K, He Y, et al. Anticubilin antisense RNA ameliorates adriamycin- induced tubulointerstitial injury in experimental rats[J]. Am J Med Sci,2011,342(6):494-502.
|
12 |
Zou Z, Chung B, Nguyen T, et al. Linking receptor-mediated endocytosis and cell signaling: evidence for regulated intramembrane proteolysis of megalin in proximal tubule [J]. J Biol Chem,2004,279(33):34302-34310.
|
13 |
Shah M, Baterina OY Jr, Taupin V, et al. ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression [J]. J Cell Biol,2013,202(1):113-127.
|
14 |
Diwakar R, Pearson AL, Colville-Nash P, et al. The role played by endocytosis in albumin-induced secretion of TGF-beta1 by proximal tubular epithelial cells[J]. Am J Physiol Renal Physiol,2007,292(5): F1464-F1470.
|
15 |
Morita Y, Ikeguchi H, Nakamura J, et al. Complement activation products in the urine from proteinuric patients [J]. J Am Soc Nephrol,2000,11(4):700-707.
|
16 |
Gou SJ, Yuan J, Wang C, et al. Alternative complement pathway activation products in urine and kidneys of patients with ANCAassociated GN [J]. Clin J Am Soc Nephrol, 2013, 8 (11):1884-1891.
|
17 |
Nangaku M, Pippin J, Couser WG. C6 mediates chronic progression of tubulointerstitial damage in rats with remnant kidneys [J]. J Am Soc Nephrol,2002,13(4):928-936.
|
18 |
Abe K, Li K, Sacks SH, et al. The membrane attack complex,C5b-9, up regulates collagen gene expression in renal tubular epithelial cells [J]. Clin Exp Immunol,2004,136(1):60-66.
|
19 |
Chen Y, Zhang J, Guo G, et al. Induced B7-H1 expression on human renal tubular epithelial cells by the sublytic terminal complement complex C5b-9 [J]. Mol Immunol, 2009, 46(3):375-383.
|
20 |
Sheerin NS, Risley P, Abe K, et al. Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury [J]. FASEB J,2008,22(4):1065-1072.
|
21 |
Tang Z, Lu B, Hatch E, et al. C3a mediates epithelial-tomesenchymal transition in proteinuric nephropathy [J]. J Am Soc Nephrol,2009,20(3):593-603.
|
22 |
Peake PW, O'Grady S, Pussell BA, et al. C3a is made by proximal tubular HK-2 cells and activates them via the C3a receptor [J].Kidney Int,1999,56(5):1729-1736.
|
23 |
Zoja C, Donadelli R, Colleoni S, et al. Protein overload stimulates RANTES production by proximal tubular cells depending on NFkappa B activation [J]. Kidney Int,1998,53(6):1608-1615.
|
24 |
Tang S, Leung JCK, Abe K, et al. Albumin stimulates interleukin-8 expression in proximal tubular epithelial cells in vitro and in vivo[J]. J Clin Invest,2003,111(4):515-527.
|
25 |
Dizin E, Hasler U, Nlandu-Khodo S, et al. Albuminuria induces a proinflammatory and profibrotic response in cortical collecting ducts via the 24p3 receptor [J]. Am J Physiol Renal Physiol,2013,305(7): F1053-F1063.
|
26 |
Morigi M, Macconi D, Zoja C, et al. Protein overload-induced NFkappa B activation in proximal tubular cells requires H2O2 through a PKC-dependent pathway [J]. J Am Soc Nephrol, 2002, 13(5):1179-1189.
|
27 |
Rangan GK, Wang Y, Tay YC, et al. Inhibition of nuclear factorkappa B activation reduces cortical tubulointerstitial injury in proteinuric rats [J]. Kidney Int,1999,56(1):118-134.
|
28 |
Takase O, Hirahashi J, Takayanagi A, et al. Gene transfer of truncated IκBα prevents tubulointerstitial injury [J]. Kidney Int,2003,63(2):501-513.
|
29 |
Ghosh SS, Massey HD, Krieg R, et al. Curcumin ameliorates renal failure in 5/6 nephrectomized rats: role of inflammation [J]. Am J Physiol Renal Physiol,2009,296(5): F1146-F1157.
|
30 |
Thomas ME, Brunskill NJ, Harris KP, et al. Proteinuria induces tubular cell turnover:a potential mechanism for tubular atrophy[J].Kidney Int,1999,55(3):890-898.
|
31 |
Erkan E, De Leon M, Devarajan P. Albumin overload induces apoptosis in LLC-PK1 cells [J]. Am J Physiol Renal Physiol,2001,280(6): F1107-F1114.
|
32 |
Morais C, Westhuyzen J, Metharom P, et al. High molecular weight plasma proteins induce apoptosis and Fas/FasL expression in human proximal tubular cells[J]. Nephrol Dial Transplant,2005,20(1):50-58.
|
33 |
Erkan E, Devarajan P, Schwartz GJ. Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells [J]. J Am Soc Nephrol,2007,18(4):1199-1208.
|
34 |
Li X, Pabla N, Wei Q, et al. PKC-delta promotes renal tubular cell apoptosis associated with proteinuria [J]. J Am Soc Nephrol,2010,21(7):1115-1124.
|
35 |
Ohse T, Inagi R, Tanaka T, et al. Albumin induces endoplasmic reticulum stress and apoptosis in renal proximal tubular cells [J].Kidney Int,2006,70(8):1447-1455.
|
36 |
Wu X, He Y, Jing Y, et al. Albumin overload induces apoptosis in renal tubular epithelial cells through a CHOP-dependent pathway[J]. OMICS,2010,14(1):61-73.
|
37 |
Lee EK, Jeong JU, Chang JW, et al. Activation of AMP-activated protein kinase inhibits albumin-induced endoplasmic reticulum stress and apoptosis through inhibition of reactive oxygen species [J].Nephron Exp Nephrol,2012,121(1-2): e38-e48.
|
38 |
Shimizu H, Maruyama S, Yuzawa Y, et al. Anti-monocyte chemoattractant protein-1 gene therapy attenuates renal injury induced by protein-overload proteinuria [J]. J Am Soc Nephrol,2003,14(6):1496-1505.
|
39 |
Viedt C, Dechend R, Fei J, et al. MCP-1 induces inflammatory activation of human tubular epithelial cells: involvement of the transcription factors, nuclear factor-κB and activating protein 21[J]. J Am Soc Nephrol,2002,13(6):1534-1547.
|
40 |
Lai KN, Leung JC, Chan LY, et al. Interaction between proximal tubular epithelial cells and infiltrating monocytes/T cells in the proteinuric state [J]. Kidney Int,2007,71(6):526-538.
|
41 |
Yazdani S, Poosti F, Kramer AB, et al. Proteinuria triggers renal lymphangiogenesis prior to the development of interstitial fibrosis[J]. PLoS One,2012,7(11): e50209.
|
42 |
Matsui T, Yamagishi S, Ueda S, et al. Irbesartan inhibits albuminelicited proximal tubular cell apoptosis and injury in vitro [J].Protein Pept Lett,2010,17(1):74-77.
|
43 |
Takao T, Horino T, Kagawa T, et al. Effects of angiotensin Ⅱtype 1 receptor blocker on albumin-induced cell damage in human renal proximal tubular epithelial cells[J]. Am J Nephrol,2009,29(2):102-108.
|
44 |
Wolf G, Schroeder R, Ziyadeh FN, et al. Albumin up-regulates the type Ⅱtransforming growth factor-beta receptor in cultured proximal tubular cells [J]. Kidney Int,2004,66(5):1849-1858.
|
45 |
Takase O, Marumo T, Imai N, et al. NF-kappaB-dependent increase in intrarenal angiotensin Ⅱinduced by proteinuria [J].Kidney Int,2005,68(2):464-473.
|
46 |
Cao W, Zhou QG, Nie J, et al. Albumin overload activates intrarenal renin-angiotensin system through protein kinase C and NADPH oxidase- dependent pathway [J]. J Hypertens, 2011, 29(7):1411-1421.
|