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中华肾病研究电子杂志 ›› 2015, Vol. 04 ›› Issue (05) : 227 -231. doi: 10.3877/cma.j.issn.2095-3216.2015.05.002

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脂蛋白肾病的诊断与治疗
何娅妮1,(), 林利容1   
  1. 1. 400042 重庆,第三军医大学大坪医院野战外科研究所肾内科
  • 出版日期:2015-10-28
  • 通信作者: 何娅妮
  • 基金资助:
    "十二五"国家科技支撑计划项目(2011BAI10B08,2011BAI10B07)

Diagnosis and treatment of lipoprotein glomerulopathy

Yani He1,(), Lirong Lin1   

  1. 1. Department of Nephrology, Daping Hospital, Research Institute of Surgery, Third Military Medical University, Chongqing 400042, China
  • Published:2015-10-28
  • Corresponding author: Yani He
  • About author:
    Corresponding author: He Yani, Email:
引用本文:

何娅妮, 林利容. 脂蛋白肾病的诊断与治疗[J]. 中华肾病研究电子杂志, 2015, 04(05): 227-231.

Yani He, Lirong Lin. Diagnosis and treatment of lipoprotein glomerulopathy[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2015, 04(05): 227-231.

脂蛋白肾病是以蛋白尿、肾功能损伤和脂蛋白代谢异常为主要表现的一种罕见疾病,主要发病机制是载脂蛋白E基因突变。脂蛋白肾病的发病率尚不清楚。本文总结了脂蛋白肾病的病理生理机制、临床及病理表现、诊断及鉴别诊断,以及当前可能有效的治疗手段。

Lipoprotein glomerulopathy is a rare disease characterized by proteinuria, renal function insufficiency, and lipoprotein metabolism dysfunction. The main pathogenesis of the disease is apolipoprotein E (apoE) gene mutation. Lipoprotein glomerulopathy is a rare ridney disease, with its incidence being unknown. This article summarizes the pathophysiology, clinical and pathological manifestations, diagnosis and differential diagnosis of lipoprotein glomerulopathy, as well as the potential effective treatments.

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