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中华肾病研究电子杂志 ›› 2017, Vol. 06 ›› Issue (01) : 6 -8. doi: 10.3877/cma.j.issn.2095-3216.2017.01.002

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特发性结节样肾小球硬化的诊断与治疗进展
朱子璇1, 李明喜1,()   
  1. 1. 100730 北京,协和医学转化中心、中国医学科学院、北京协和医院 肾内科
  • 收稿日期:2017-01-10 出版日期:2017-02-28
  • 通信作者: 李明喜
  • 基金资助:
    国家重点研发计划罕见病临床队列研究(2016YFC0901500)

Progress in diagnosis and treatment for idiopathic nodular glomerulosclerosis

Zixuan Zhu1, Mingxi Li1,()   

  1. 1. Department of Nephrology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China
  • Received:2017-01-10 Published:2017-02-28
  • Corresponding author: Mingxi Li
  • About author:
    Corresponding author: Li Mingxi, Email:
引用本文:

朱子璇, 李明喜. 特发性结节样肾小球硬化的诊断与治疗进展[J]. 中华肾病研究电子杂志, 2017, 06(01): 6-8.

Zixuan Zhu, Mingxi Li. Progress in diagnosis and treatment for idiopathic nodular glomerulosclerosis[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2017, 06(01): 6-8.

特发性结节样肾小球硬化(idiopathic nodular glomerulosclerosis,ING)是一种罕见的肾脏疾病,发病率低,临床表现非特异。该病病理表现与糖尿病肾病相似,以肾小球结节样硬化为特征性表现,但于非糖尿病人群中发病。确诊及鉴别诊断需要肾组织免疫病理及电镜检查。至今对其机制、病因的讨论仍存在较多争议。本文汇总国内外针对ING的相关研究文献,对该病危险因素、诊断及治疗进展进行概述及阐释。

Idiopathic nodular glomerulosclerosis (ING) is a rare kidney disease which has a low morbidity with no specific manifestations. It resembles nodular diabetic glomerulosclerosis in pathology features but occurs in nondiabetic patients. The diagnosis and differential diagnosis mainly rely on the immunofluorescence and electron microscopic (EM) findings. Unfortunately, controversies still exist on the exact mechanism and etiology of ING. This article mainly discussed the risk factors, diagnosis and treatment of ING based on the current studies worldwide.

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