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中华肾病研究电子杂志 ›› 2023, Vol. 12 ›› Issue (06) : 357 -359. doi: 10.3877/cma.j.issn.2095-3216.2023.06.011

病例报告

炎症性肠病伴发肾脏累及:一例报告并文献复习
向子猷, 丁家荣, 李璐, 汪海燕, 赖学莉, 郭志勇()   
  1. 200433 上海,海军军医大学第一附属医院长海医院肾内科
  • 收稿日期:2022-06-24 出版日期:2023-12-28
  • 通信作者: 郭志勇
  • 基金资助:
    海军军医大学第一附属医院"234学科攀登计划"(2020YXK041)

Renal involvement in inflammatory bowel disease: a case report with literature review

Ziyou Xiang, Jiarong Ding, Lu Li   

  • Received:2022-06-24 Published:2023-12-28
引用本文:

向子猷, 丁家荣, 李璐, 汪海燕, 赖学莉, 郭志勇. 炎症性肠病伴发肾脏累及:一例报告并文献复习[J]. 中华肾病研究电子杂志, 2023, 12(06): 357-359.

Ziyou Xiang, Jiarong Ding, Lu Li. Renal involvement in inflammatory bowel disease: a case report with literature review[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2023, 12(06): 357-359.

炎症性肠病(inflammatory bowel disease,IBD)是一种非特异性的肠道慢性炎症,主要包括溃疡性结肠炎和克罗恩病。IBD肠外表现可累及多个器官,可发生在疾病的任何阶段,甚至可以作为IBD的首发症状。IBD同样也会对泌尿系统累及,根据文献报道,IBD泌尿系统病变患病率不到2%[1],很容易在临床诊疗过程中被忽视。泌尿系统累及主要是肾脏,发生可能的原因是与肠道炎症性疾病有相同的免疫机制,并且与肠道炎症活动直接相关。本研究对1例炎症性肠病伴发肾脏累及患者进行报道,并总结既往国内外报道的病例及临床特点,以帮助临床医师提高对IBD肾脏累及的认识,旨在探讨IBD肾脏累及的分类,发病机制及治疗。

图1 肠镜检查图像注:A:升结肠;B:盲肠;C:升结肠;图中可见盲肠变形,盲肠至升结肠黏膜多发息肉样增生呈鹅卵石样改变伴有多发浅溃疡形成,结肠病变呈节段性,之间可见基本正常黏膜
表1 克罗恩病和溃疡性结肠炎患者中出现肾脏累及的患病率
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