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中华肾病研究电子杂志 ›› 2024, Vol. 13 ›› Issue (04) : 234 -235. doi: 10.3877/cma.j.issn.2095-3216.2024.04.010

病例报告

奈玛特韦片/利托那韦片组合包装治疗一例血透患者伴发重型新冠肺炎
彭丽敏1, 刘键1,()   
  1. 1. 300381 天津康复疗养中心血液净化中心
  • 收稿日期:2023-03-24 出版日期:2024-08-28
  • 通信作者: 刘键

Nirmatrelvir plus ritonavir treatment of severe COVID-19 in a hemodialysis patient

Limin Peng, Jian Liu()   

  • Received:2023-03-24 Published:2024-08-28
  • Corresponding author: Jian Liu
引用本文:

彭丽敏, 刘键. 奈玛特韦片/利托那韦片组合包装治疗一例血透患者伴发重型新冠肺炎[J]. 中华肾病研究电子杂志, 2024, 13(04): 234-235.

Limin Peng, Jian Liu. Nirmatrelvir plus ritonavir treatment of severe COVID-19 in a hemodialysis patient[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2024, 13(04): 234-235.

血液透析患者免疫功能低下是感染的高发人群,我科收治1例血透合并重型新冠肺炎的老年肥胖患者,应用奈玛特韦片/利托那韦片组合包装康复出院。现将该病例诊治情况报告如下。

图1 治疗前后肺CT检查对比注:A、C和E:患者入院时肺CT检查影像;B、D和F:患者出院前肺CT检查影像;A、C和E图中箭头所示为左肺上下叶见大片状渗出病变,范围较广;B、D和F:左肺见少许小斑片状模糊高密度影;A与B、C与D、E与F患者入院前后肺CT检查图像两两对比可见原左肺箭头所示部位的病变范围明显缩小、明显吸收好转
[1]
欧阳彦,陈孜璟,章倩莹,等. 慢性肾脏病人群的新型冠状病毒感染临床诊治建议(瑞金医院2023版) [J]. 内科理论与实践2023, 18 (1): 28-33.
[2]
Hiremath S, McGuinty M, Argyropoulos C, et al. Prescribing nirmatrelvir/ritonavir for COVID-19 in advanced CKD [J]. Clin J Am Soc Nephrol, 2022, 17(8): 1247-1250.
[3]
Lingscheid T, Kinzig M, Krüger A, et al. Pharmacokinetics of nirmatrelvir and ritonavir in COVID-19 patients with end-stage renal disease on intermittent hemodialysis [J]. Antimicrob Agents Chemother, 2022, 66(11): e0122922.
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