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中华肾病研究电子杂志 ›› 2026, Vol. 15 ›› Issue (03) : 173 -175. doi: 10.3877/cma.j.issn.2095-3216.2026.03.009

病例报告

以腹痛为首发表现的系统性红斑狼疮一例
聂飒飒1, 于祥1, 王自英2, 冯哲1, 林淑芃1,()   
  1. 1100853 北京,解放军总医院肾脏病医学部、肾脏疾病全国重点实验室、国家慢性肾病临床医学研究中心、重症肾脏疾病器械与中西医药物研发北京市重点实验室、数智中医泛血管疾病防治北京市重点实验室、国家中医药管理局高水平中医药重点学科(zyyzdxk-2023310)
    2641000 内江市第二人民医院肾内科
  • 收稿日期:2025-07-30 出版日期:2026-06-28
  • 通信作者: 林淑芃

Systemic lupus erythematosus with abdominal pain as the initial manifestation: a case report

Sasa Nie, Xiang Yu, Ziying Wang   

  • Received:2025-07-30 Published:2026-06-28
引用本文:

聂飒飒, 于祥, 王自英, 冯哲, 林淑芃. 以腹痛为首发表现的系统性红斑狼疮一例[J/OL]. 中华肾病研究电子杂志, 2026, 15(03): 173-175.

Sasa Nie, Xiang Yu, Ziying Wang. Systemic lupus erythematosus with abdominal pain as the initial manifestation: a case report[J/OL]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2026, 15(03): 173-175.

图1 肾脏组织病理学注:A:7个肾小球见1处纤维细胞性新月体,黄色箭头处(PAS染色×400);B:多灶性、轻度炎细胞浸润(黄色箭头处),炎细胞以淋巴/单核细胞为主,见多灶性、轻度纤维化(PAS染色×200);C:上皮下、内皮下可见嗜复红物质沉积,基底膜明显增厚,可见钉突及链环样变(过碘酸-六胺银染色×400);D:肾小管:上皮细胞微绒毛脱落、线粒体肿胀、空泡变性(电镜);E:IgG(+2)沿毛细血管袢颗粒样沉积(免疫荧光×400);F:C3(+2)沿毛细血管袢颗粒样沉积(免疫荧光×400)
图2 狼疮胃肠道CT影像注:A:腹部增强CT提示肠系膜血管影的"梳状征";B:腹部增强CT提示肠壁分层的"靶征",表现为内外两层密度较高,中间层密度较低;C:泌尿系超声可见右肾盂扩张,右肾盂前后径2.3 cm;D:泌尿系超声:见右侧输尿管扩张,右输尿管0.9 cm
[1]
Tian XP, Zhang X. Gastrointestinal involvement in systemic lupus erythematosus: insight into pathogenesis, diagnosis and treatment [J]. World J Gastroenterol, 2010, 16(24): 2971-2977.
[2]
杨华夏. 系统性红斑狼疮的胃肠道损伤[J]. 中国实用内科杂志2021, 41(9): 753-756.
[3]
中华医学会风湿病学分会. 系统性红斑狼疮诊疗指南(2020年版)[J]. 中华内科杂志2020, 59(3): 172-185.
[4]
Frittoli RB, Vivaldo JF, Costallat LTL, et al. Gastrointestinal involvement in systemic lupus erythematosus: a systematic review [J]. J Transl Autoimmun, 2021, 4: 100106.
[5]
Ju JH, Min JK, Jung CK, et al. Lupus mesenteric vasculitis can cause acute abdominal pain in patients with SLE [J]. Nat Rev Rheumatol, 2009, 5(5): 273-281.
[6]
Leone P, Prete M, Malerba E, et al. Lupus vasculitis: an overview [J]. Biomedicines, 2021, 9(11): 1626.
[7]
Ceccato F, Salas A, Góngora V, et al. Chronic intestinal pseudo-obstruction in patients with systemic lupus erythematosus: report of four cases [J]. Clin Rheumatol, 2008, 27(3): 399-402.
[8]
Hill PA, Dwyer KM, Power DA. Chronic intestinal pseudo-obstruction in systemic lupus erythematosus due to intestinal smooth muscle myopathy [J]. Lupus, 2000, 9(6): 458-463.
[9]
Alsolaimani R. Mesenteric vasculitis and urinary system involvement presenting as the initial manifestations of systemic lupus erythematosus treated successfully with glucocorticoids and rituximab: a case report [J]. Cureus, 2022, 14(11): e31474.
[10]
Fotis L, Baszis KW, French AR, et al. Mesenteric vasculitis in children with systemic lupus erythematosus [J]. Clin Rheumatol, 2015, 35(3): 785-793.
[11]
Perlemuter G, Chaussade S, Wechsler B, et al. Chronic intestinal pseudo-obstruction in systemic lupus erythematosus [J]. Gut, 1998, 43(1): 117-122.
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