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中华肾病研究电子杂志 ›› 2013, Vol. 02 ›› Issue (03) : 110 -114. doi: 10.3877/cma.j.issn.2095-3216.2013.03.001

述评

重视急性肾损伤的临床与基础研究
陈香美1,(), 冯哲   
  1. 1.100853 北京,解放军总医院肾脏病科 全军肾脏病研究所 肾脏疾病国家重点实验室
  • 出版日期:2013-06-15
  • 通信作者: 陈香美
  • 基金资助:
    北京市科学技术委员会‘首都临床特色应用研究’专项资助课题(Z131107002213011)

Emphasis on clinical and basic research of acute kidney injury

Xiang-mei CHEN1,(), Zhe FENG1   

  1. 1.Department of Nephrology, Kidney Institute of Chinese People 's Liberation Army, State Key Laboratory of Kidney Disease, Chinese People 's Liberation Army General Hospital, Beijing 100853, China
  • Published:2013-06-15
  • Corresponding author: Xiang-mei CHEN
引用本文:

陈香美, 冯哲. 重视急性肾损伤的临床与基础研究[J/OL]. 中华肾病研究电子杂志, 2013, 02(03): 110-114.

Xiang-mei CHEN, Zhe FENG. Emphasis on clinical and basic research of acute kidney injury[J/OL]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2013, 02(03): 110-114.

急性肾损伤(AKI)是临床常见的急危重症,住院患者AKI发病率、病死率逐年增高,消耗大量医疗资源。如何防治AKI的发生、发展已成为当前肾脏病研究工作中的重点和热点。重视AKI病因疾病谱等流行病学特征、发病机制、早期诊断方法、临床治疗的基础研究,开展全国多中心、大样本、前瞻性的AKI防治的循证医学研究,对我国AKI的预防及预后具有重要意义。现就目前国内外AKI发病机制的研究进展和诊治现状进行述评。

Acute kidney injury (AKI) is a common clinical acute critical illness. The incidence and mortality of AKI in hospitalized patients is increasing year by year, which consumes large amounts of health care resources. How to prevent the occurrence and development of AKI has now become the focus and hotspots of the nephrology research work. Emphasis should be paid on basic researches of not only the epidemiological characteristics including AKI disease spectrum of etiology, etc., but also the pathogenesis,early diagnosis, and clinical treatment. Besides, evidence-based national multi-centeral, large sample, and prospective medical research on AKI prevention and treatment should be conducted. These will be of great significance on the prevention of and prognosis of AKI. In this paper, we have made a review and outlook on current progress of domestic and international study of the pathogenesis as well as the status of diagnosis and treatment of AKI.

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