以皮肤紫癜为表现的干燥综合征一例

doi:10.3877/cma.j.issn.2095-3216.2014.03.011

中华肾病研究电子杂志 ›› 2014, Vol. 03 ›› Issue (03) : 166 -167. doi: 10.3877/cma.j.issn.2095-3216.2014.03.011

所属专题：经典病例；

病例报告

以皮肤紫癜为表现的干燥综合征一例

林利容¹, 张建国¹, 肖菲¹, 戴欢子¹, 张炜炜¹, 杨聚荣¹, 李开龙¹, 何娅妮¹^,^†(

)

1.400042 重庆,第三军医大学第三附属医院野战外科研究所肾内科

出版日期:2014-06-15
通信作者: 何娅妮

A patient with Sjögren syndrome manifesting as skin purpura

Lirong Lin, Jianguo Zhang, Fei Xiao, Huanzi Dai, Weiwei Zhang, Jurong Yang, Kailong Li, Yani He^†()

Published:2014-06-15
Corresponding author: Yani He

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林利容, 张建国, 肖菲, 戴欢子, 张炜炜, 杨聚荣, 李开龙, 何娅妮. 以皮肤紫癜为表现的干燥综合征一例[J/OL]. 中华肾病研究电子杂志, 2014, 03(03): 166-167.

Lirong Lin, Jianguo Zhang, Fei Xiao, Huanzi Dai, Weiwei Zhang, Jurong Yang, Kailong Li, Yani He. A patient with Sjögren syndrome manifesting as skin purpura[J/OL]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2014, 03(03): 166-167.

图1 以皮肤紫癜为表现的干燥综合征患者肾组织病理图片注:A 为光镜下间质局灶单个核细胞浸润,间质增宽、纤维化,肾小管正常结构消失(PAS×100);B 为免疫荧光IgA 沿毛细血管袢及系膜区沉积(IF×200)

1	Sisto M, Lisi S, Lofrumento D, et al. Autoantibodies from Sjögren's syndrome trigger apoptosis in salivary gland cell line [J]. Ann N Y Acad Sci,2007,1108:418-425.
2	Soy M, Piskin S. Cutaneous findings in patients with primary Sjogren's syndrome [J]. Clin Rheumatol, 2007, 26(8): 1350-1352.
3	Elfatoiki FZ, Funck Brentano E, Blanc F, et al. Nodular cutaneous amyloidosis associated with Sjögren's syndrome [J]. Ann Dermatol Venereol,2013,140(5):378-381.
4	Meijer JM, Schonland SO, Palladini G, et al. Sjögren's syndrome and localized nodular cutaneous amyloidosis: coincidence or a distinct clinical entity [J] ? Arthritis Rheum,2008,58(7):1992-1999.
5	Ramos-Casals M, Anaya JM, García-Carrasco M, et al. Cutaneous vasculitis in primary Sjögren syndrome: classification and clinical significance of 52 patients [J]. Medicine (Baltimore), 2004, 83(2):96-106.
6	Toumeh A, Josh N, Narwal R, et al. Refractory thrombotic thrombocytopenic purpura associated with primary Sjögren syndrome treated with rituximab: a case report [J]. Am J Ther, 2014, 21(2): e56-e60.

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