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中华肾病研究电子杂志 ›› 2014, Vol. 03 ›› Issue (03) : 160 -165. doi: 10.3877/cma.j.issn.2095-3216.2014.03.010

综述

腹膜透析患者腹膜转运功能的影响因素及其维护
曹雪莹1, 周建辉1, 蔡广研1, 陈香美1,()   
  1. 1.100853 北京,解放军总医院肾脏病科、解放军肾脏病研究所、肾脏疾病国家重点实验室、国家慢性肾病临床医学研究中心
  • 出版日期:2014-06-15
  • 通信作者: 陈香美
  • 基金资助:
    “十二五”国家科技支撑计划课题“腹膜透析医用材料及配套设备研发”(2014BAI11B16)解放军总医院四百工程基金“腹膜透析救治高出血风险的肾衰竭”(MJ201407)

Influence factors and maintenance of peritoneal transport function in peritoneal dialysis patients

Xueying Cao1, Jianhui Zhou1, Guangyan Cai1, Xiangmei Chen1,()   

  1. 1.Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center of Kidney Diseases, Beijing 100853, China
  • Published:2014-06-15
  • Corresponding author: Xiangmei Chen
引用本文:

曹雪莹, 周建辉, 蔡广研, 陈香美. 腹膜透析患者腹膜转运功能的影响因素及其维护[J/OL]. 中华肾病研究电子杂志, 2014, 03(03): 160-165.

Xueying Cao, Jianhui Zhou, Guangyan Cai, Xiangmei Chen. Influence factors and maintenance of peritoneal transport function in peritoneal dialysis patients[J/OL]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2014, 03(03): 160-165.

腹膜透析是终末期肾脏病患者的重要替代治疗方式,尽管其短期技术存活率较好,但长期治疗后导致的超滤衰竭,仍然是退出治疗的主要原因。 葡萄糖透析液所致的腹膜功能下降与其血管增生和腹膜纤维化密切相关,但是糖尿病、尿毒症毒素、药物、腹膜炎、残余肾功能等诸多因素也影响着腹膜的属性。 现就相关的影响因素及其可能的干预方法进行综述。

Peritoneal dialysis is an important replacement therapy for end-stage renal disease.Although the short-term technical survival of peritoneal dialysis is good, but ultrafiltration failure after longterm peritoneal dialysis is still the main cause for withdrawal of peritoneal dialysis treatment. The decline in peritoneal function can be attributed to its blood vessel proliferation and peritoneal fibrosis caused by glucose dialysate. However, the peritoneal function may also be affected by many other factors including diabetes,uremic toxins, drugs, peritonitis, and residual renal function. This review has been made regarding the related influencing factors and the possible intervention methods.

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