多发性骨髓瘤(MM)是浆细胞系异常增生的恶性疾病，常伴有肾脏损害、高钙血症、骨病、高粘滞血症、贫血、感染、血栓等；伴有肾脏损害的患者约占50%，其肾脏损害多表现为管型肾病，其中约9%的患者需要透析治疗。骨髓瘤肾病的西医治疗主要包括：水化、避免肾损害的药物使用，血浆置换、血液透析以及原发病的化疗及干细胞移植。中医治疗主要是在西医治疗的基础上进行的中医辨证论治，主要效果在于增强机体免疫力、提高化疗敏感性、促进正常造血功能恢复、减轻主观症状、减少西医治疗的并发症等。

Multiple myeloma (MM) is a malignant disease with abnormal proliferation of plasma cells, often accompanied with renal impairment (RI), hypercalcemia, bone disease, hyperviscositemia, anemia, infection, thrombosis, etc. Patients with RI account for about 50% of MM. Most RI manifested as cast nephropathy, of which about 9% need dialysis treatment. The western medicine treatment for RI of MM mainly includes adequate hydration, avoidance of using agents that contribute to renal damage, plasma exchange, hemodialysis, chemotherapy for primary disease, and stem cell transplantation; while the traditional Chinese medicine treatment for RI of MM is based on the western medicine treatment, providing treatment on the base of syndrome differentiation, the main effects of which were comprised of enhancing immunity, improving chemotherapy sensitivity, promoting recovery of normal hematopoietic function, reducing subjective symptoms, and decreasing complications of western medicine treatment.