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中华肾病研究电子杂志 ›› 2017, Vol. 06 ›› Issue (03) : 138 -141. doi: 10.3877/cma.j.issn.2095-3216.2017.03.009

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综述

糖尿病肾病和非糖尿病肾病鉴别诊断的研究进展
王倩1, 董哲毅1, 周建辉1, 刘晓敏1, 陈香美1,()   
  1. 1. 100853 北京,解放军总医院肾脏病科、解放军肾脏病研究所、肾脏疾病国家重点实验室、国家慢性肾病临床医学研究中心
  • 收稿日期:2017-04-20 出版日期:2017-06-28
  • 通信作者: 陈香美
  • 基金资助:
    解放军总医院基金(16KMM08,2016FC-TSYS-1043); 国家重点研发计划(2016YFC1305502); 国家自然科学基金(61471399,81473531); 吴阶平医学基金会临床科研专项资助基金(320.6750.16191)

Progress of research on differential diagnosis of diabetic nephropathy and non-diabetic renal disease

Qian Wang1, Zheyi Dong1, Jianhui Zhou1, Xiaomin Liu1, Xiangmei Chen1,()   

  1. 1. Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing 100853, China
  • Received:2017-04-20 Published:2017-06-28
  • Corresponding author: Xiangmei Chen
  • About author:
    Corresponding author: Chen Xiangmei, Email:
引用本文:

王倩, 董哲毅, 周建辉, 刘晓敏, 陈香美. 糖尿病肾病和非糖尿病肾病鉴别诊断的研究进展[J/OL]. 中华肾病研究电子杂志, 2017, 06(03): 138-141.

Qian Wang, Zheyi Dong, Jianhui Zhou, Xiaomin Liu, Xiangmei Chen. Progress of research on differential diagnosis of diabetic nephropathy and non-diabetic renal disease[J/OL]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2017, 06(03): 138-141.

糖尿病肾病和非糖尿病肾病鉴别诊断的金标准为肾穿刺活检的病理,但肾活检为有创检查,患者接受程度较低。临床实际应用中往往根据糖尿病视网膜病变、蛋白尿、糖尿病病程、血尿、收缩压等进行鉴别诊断。近年来对这些传统临床指标有了新认识,具有鉴别诊断意义的无创性生物标志物和影像学新技术的研究进展也逐渐增多,这些都为疾病的鉴别诊断提供了更广阔的思路。

The gold standard for differential diagnosis of diabetic nephropathy and non-diabetic renal disease is the pathology of renal biopsy. It′s difficult for patients to accept the renal biopsy as an invasive examination. Thus, in clinical practice, clinicians often make the differential diagnosis based on diabetic retinopathy, proteinuria, diabetes duration, hematuria, and systolic blood pressure, etc. In recent years, a mounting understanding for the traditional clinical indicators has appeared. At the same time, new noninvasive biomarkers and imaging techniques contributing to differential diagnosis have also increased. All of these new findings have provided a broader horizon for the differential diagnosis of diabetic kidney diseases.

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