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中华肾病研究电子杂志 ›› 2020, Vol. 09 ›› Issue (05) : 220 -223. doi: 10.3877/cma.j.issn.2095-3216.2020.05.006

所属专题: 文献

综述

特发性膜性肾病并发静脉血栓栓塞症的研究进展
鲁春蕾1, 刘昌华1,()   
  1. 1. 225001 江苏省扬州市,江苏省苏北人民医院
  • 收稿日期:2020-01-09 出版日期:2020-10-28
  • 通信作者: 刘昌华

Research progress of idiopathic membranous nephropathy complicated with venous thromboembolism

Chunlei Lu1, Changhua Liu1,()   

  1. 1. Department of Nephrology, Northern Jiangsu People′s Hospital Affiliated to Yangzhou University, Yangzhou 225001, Jiangsu Province, China
  • Received:2020-01-09 Published:2020-10-28
  • Corresponding author: Changhua Liu
  • About author:
    Corresponding author: Liu Changhua, Email:
引用本文:

鲁春蕾, 刘昌华. 特发性膜性肾病并发静脉血栓栓塞症的研究进展[J]. 中华肾病研究电子杂志, 2020, 09(05): 220-223.

Chunlei Lu, Changhua Liu. Research progress of idiopathic membranous nephropathy complicated with venous thromboembolism[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2020, 09(05): 220-223.

特发性膜性肾病患者常合并有静脉血栓栓塞症(venous thromboembolism,VTE),包括肺血栓栓塞症(pulmonary thromboembolism,PTE)、深静脉血栓(deep venous thrombosis,DVT)等。VTE不仅是造成特发性膜性肾病患者病情迁延和死亡的重要原因,而且还影响肾穿刺活检,从而导致不能明确部分患者的病理分型,对疾病的疗效和预后均有较大影响。目前在特发性膜性肾病患者易于并发VTE的机制、以及非VTE患者的预防性抗凝治疗方面尚存争议。本文对特发性膜性肾病并发VTE的发病机制、诊断和治疗进展作一综述。

Patients with idiopathic membranous nephropathy (IMN) are often complicated with venous thromboembolism (VTE), including pulmonary thromboembolism (PTE), and deep venous thrombosis (DVT), etc. VTE is not only an important cause for disease prolongation and death of patients with IMN, but also affects renal biopsy so much that some patients′ pathological types can′t be clarified, which has a great impact on the efficacy and prognosis of the disease. At present, there are still controversies regarding not only the mechanism by which patients with IMN are prone to be complicated with VTE, but also the preventive anticoagulation treatment for non-VTE patients. This article reviewed the research progress of pathogenesis, diagnosis, and treatment of IMN complicated by VTE.

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