切换至 "中华医学电子期刊资源库"

中华肾病研究电子杂志 ›› 2023, Vol. 12 ›› Issue (04) : 220 -223. doi: 10.3877/cma.j.issn.2095-3216.2023.04.008

综述

丝氨酸蛋白酶Corin与肾脏疾病的关系研究进展
张艳如, 苏晓乐, 王利华()   
  1. 030001 太原,山西医科大学第二医院肾内科
  • 收稿日期:2022-09-15 出版日期:2023-08-28
  • 通信作者: 王利华
  • 基金资助:
    国家青年科学基金项目(2F12020028)

Progress of research on the relationship between serine protease corin and kidney disease

Yanru Zhang, Xiaole Su, Lihua Wang()   

  1. Department of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
  • Received:2022-09-15 Published:2023-08-28
  • Corresponding author: Lihua Wang
引用本文:

张艳如, 苏晓乐, 王利华. 丝氨酸蛋白酶Corin与肾脏疾病的关系研究进展[J]. 中华肾病研究电子杂志, 2023, 12(04): 220-223.

Yanru Zhang, Xiaole Su, Lihua Wang. Progress of research on the relationship between serine protease corin and kidney disease[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2023, 12(04): 220-223.

Corin是一种丝氨酸蛋白酶,广泛分布于肾脏上皮组织,可通过活化心房利钠肽而具有利钠、排水、舒张血管等作用。本文综述Corin与高血压、慢性肾脏病等疾病的关系研究进展,以探讨其作为肾脏疾病生物标志物的可能性。

Corin is a serine protease widely distributed in the epithelial tissues of the kidney. It can activate atrial natriuretic peptide, having natriuretic, water excretion, and vasodilation effects. This article reviewed the progress of research on the relationship between corin and diseases such as hypertension and chronic kidney disease, in order to explore its potential as a biomarker for kidney disease.

[1]
Boroń D, Kornacki J, Gutaj P, et al. Corin-the early marker of preeclampsia in pregestational diabetes mellitus [J]. J Clin Med, 2022, 12(1): 61.
[2]
王兰,牛泽家馨,郭艳杰,等. Corin基因多态性与血压钠钾反应性的相关性分析[J]. 西安交通大学学报(医学版), 2023, 44(1): 22-29.
[3]
赵谊昶,刘金秋,夏云龙,等. PCSK6-Corin-ANP轴在心血管疾病诊治中的进展[J]. 中华心力衰竭和心肌病杂志2022, 6(3): 251-256.
[4]
Shi J, Wu L, Chen Y, et al. Association between corin methylation and hypertension in Chinese adults [J]. Postgrad Med J, 2022, Epub ahead of print.
[5]
Parcha V, Irvin MR, Lange LA, et al. Corin missense variants, blood pressure, and hypertension in 11 322 black individuals: insights from REGARDS and the Jackson Heart Study [J]. J Am Heart Assoc, 2022, 11(12): e025582.
[6]
王九龙,卢青,丁世芳. 急性冠脉综合征患者PCSK6、Corin、NT-proBNP表达水平与冠状动脉病变程度及短期预后的相关性研究[J]. 华南国防医学杂志2022, 36(5): 335-342, 350.
[7]
Lefèvre M, Cavailhès J, Ferri C, et al. CORIN KneeTec DeepDishTM: functional outcomes after a follow-up of 12 months and comparison with the STRYKER Triathlon PS [J]. Acta Orthop Belg, 2022, 88(1): 61-71.
[8]
Zhang X, Gu X, Zhang Y, et al. Corin: a key mediator in sodium homeostasis, vascular remodeling, and heart failure [J]. Biology (Basel), 2022, 11(5): 717.
[9]
Zhang W, Zhou Y, Dong Y, et al. Correlation between N-terminal pro-atrial natriuretic peptide, corin, and target organ damage in hypertensive disorders of pregnancy [J]. J Clin Hypertens (Greenwich), 2022, 24(5): 644-651.
[10]
Khoury EE, Fokra A, Kinaneh S, et al. Distribution of cardiac and renal corin and proprotein convertase subtilisin/kexin-6 in the experimental model of cardio-renal syndrome of various severities [J]. Front Physiol, 2021, 12: 673497.
[11]
Wang M, Lee-Kim VS, Atri DS, et al. Rare, damaging DNA variants in corin and risk of coronary artery disease: insights from functional genomics and large-scale sequencing analyses [J]. Circ Genom Precis Med, 2021, 14(5): e003399.
[12]
胡健伟,喻茜,刘丽,等. 人血清Corin蛋白水平与妊娠期高血压病例对照研究[J]. 江苏预防医学2021, 32(5): 633-635.
[13]
Genç Yavuz B, Sögüt ÖÇolak Ş, et al. Low serum corin levels predict end-organ damage in patients with hypertensive crisis [J]. Anatol J Cardiol, 2021, 25(8): 536-543.
[14]
Yan W, Wu F, Morser J, et al. Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme [J]. Proc Natl Acad Sci USA, 2000, 97(15): 8525-8529.
[15]
钱琪钰,莫兴波,段程成,等. 中国汉族人群血清可溶性Corin水平与超重或肥胖的关系[J]. 现代预防医学2021, 48(13): 2447-2451.
[16]
Chen S, Cao P, Dong N, et al. PCSK6-mediated corin activation is essential for normal blood pressure [J]. Nat Med, 2015, 21(9): 1048-1053.
[17]
Niu Y, Zhang S, Gu X, et al. Recombinant soluble corin improves cardiac function in mouse models of heart failure [J]. J Am Heart Assoc, 2021, 10(7): e019961.
[18]
Schefold JC, Filippatos G, Hasenfuss G, et al. Heart failure and kidney dysfunction: epidemiology, mechanisms and management [J]. Nat Rev Nephrol, 2016, 12(10): 610-623.
[19]
Wang J, Mi Y, Wu S, et al. Exosomes from adipose-derived stem cells protect against high glucose-induced erectile dysfunction by delivery of corin in a streptozotocin-induced diabetic rat model [J]. Regen Ther, 2020, 14: 227-233.
[20]
Sullivan RD, Houng AK, Gladysheva IP, et al. Corin overexpression reduces myocardial infarct size and modulates cardiomyocyte apoptotic cell death [J]. Int J Mol Sci, 2020, 21(10): 3456.
[21]
Ozer A, Tolun F, Aslan F, et al. The role of G protein-associated estrogen receptor (GPER) 1, corin, raftlin, and estrogen in etiopathogenesis of intrauterine growth retardation [J]. J Matern Fetal Neonatal Med, 2021, 34(5): 755-760.
[22]
Wang W, Liao X, Fukuda K, et al. Corin variant associated with hypertension and cardiac hypertrophy exhibits impaired zymogen activation and natriuretic peptide processing activity [J]. Circ Res, 2008, 103(5): 502-508.
[23]
Cui Y, Wang W, Dong N, et al. Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy [J]. Nature, 2012, 484(7393): 246-250.
[24]
Wright JS, Jones A, Farmer B, et al. POSS-enhanced colorless organic/inorganic nanocomposite (CORIN®) for atomic oxygen resistance in low earth orbit [J]. CEAS Space J, 2021, 13(3): 399-413.
[25]
Lee SJ, Lee DH, Kim HW. Novel antihypertension mechanism of β-glucan by corin and ANP-mediated natriuresis in mice [J]. Mycobiology, 2020, 48(5): 399-409.
[26]
Xue M, Shi Y, Pang A, et al. Corin plays a protective role via upregulating MAPK and downregulating eNOS in diabetic nephropathy endothelial dysfunction [J]. FASEB J, 2020, 34(1): 95-106.
[27]
Celik S, Karbalaei-Sadegh M, Rådegran G, et al. Functional screening identifies microRNA regulators of corin activity and atrial natriuretic peptide biogenesis [J]. Mol Cell Biol, 2019, 39(23): e00271-19.
[28]
Polzin D, Kaminski HJ, Kastner C, et al. Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases [J]. Kidney Int, 2010, 78(7): 650-659.
[29]
Yin R, Qiu C, Shen Q, et al. Corin is regulated by circ-0012397/miR-200a-3p and inhibits the oxygen-glucose deprivation-induced apoptosis of SHSY5Y neuroblastoma cells [J]. Ann Transl Med, 2022, 10(22): 1242.
[30]
Choi MR, Fernández BE. Protective renal effects of atrial natriuretic peptide: where are we now? [J]. Front Physiol, 2021, 12: 680213.
[31]
Tripathi R, Sullivan RD, Fan TM, et al. Cardiac-specific overexpression of catalytically inactive corin reduces edema in contractile dysfunction and death in mice with dilated cardiomyopathy [J]. Int J Mol Sci, 2019, 21(1): 203.
[32]
叶静,尹成龙,曹克将. 血清Corin对急性心肌梗死突发患者的诊断价值及其预后的影响[J]. 中国煤炭工业医学杂志2020, 23(2): 209-213.
[33]
Matos ACC, Requiao Moura LR, Borrelli M, et al. Impact of machine perfusion after long static cold storage on delayed graft function incidence and duration and time to hospital discharge [J]. Clin Transplant, 2018, 32(1): doi: 10.1111/ctr.13130.
[34]
Hu X, Su M, Lin J, et al. Corin is downregulated in renal ischemia/reperfusion injury and is associated with delayed graft function after kidney transplantation [J]. Dis Markers, 2019, 2019: 9429323.
[1] 杨水华, 何桂丹, 覃桂灿, 梁蒙凤, 罗艳合, 李雪芹, 唐娟松. 胎儿孤立性完全型肺静脉异位引流的超声心动图特征及高分辨率血流联合时间-空间相关成像的应用[J]. 中华医学超声杂志(电子版), 2023, 20(10): 1061-1067.
[2] 王得晨, 杨康, 杨自杰, 归明彬, 屈莲平, 张小凤, 高峰. 结直肠癌微卫星稳定状态和程序性死亡、吲哚胺2,3-双加氧酶关系的研究进展[J]. 中华普通外科学文献(电子版), 2023, 17(06): 462-465.
[3] 彭旭, 邵永孚, 李铎, 邹瑞, 邢贞明. 结肠肝曲癌的诊断和外科治疗[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 108-110.
[4] 马伟强, 马斌林, 吴中语, 张莹. microRNA在三阴性乳腺癌进展中发挥的作用[J]. 中华普外科手术学杂志(电子版), 2024, 18(01): 111-114.
[5] 陈垚, 徐伯群, 高志慧. 改良式中间上入路根治术治疗甲状腺癌的有效性安全性研究[J]. 中华普外科手术学杂志(电子版), 2023, 17(06): 619-622.
[6] 孔博, 张璟, 吕珂. 超声技术在复杂腹壁疝诊治中的作用[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 670-673.
[7] 姜明, 罗锐, 龙成超. 闭孔疝的诊断与治疗:10年73例患者诊疗经验总结[J]. 中华疝和腹壁外科杂志(电子版), 2023, 17(06): 706-710.
[8] 袁媛, 赵良平, 刘智慧, 张丽萍, 谭丽梅, 閤梦琴. 子宫内膜癌组织中miR-25-3p、PTEN的表达及与病理参数的关系[J]. 中华临床医师杂志(电子版), 2023, 17(9): 1016-1020.
[9] 陆志峰, 周佳佳, 梁舒. 虚拟现实技术在治疗弱视中的临床应用研究进展[J]. 中华临床医师杂志(电子版), 2023, 17(08): 891-895.
[10] 李田, 徐洪, 刘和亮. 尘肺病的相关研究进展[J]. 中华临床医师杂志(电子版), 2023, 17(08): 900-905.
[11] 岳瑞雪, 孔令欣, 郝鑫, 杨进强, 韩猛, 崔国忠, 王建军, 张志生, 孔凡庭, 张维, 何文博, 李现桥, 周新平, 徐东宏, 胡崇珠. 乳腺癌HER2蛋白表达水平预测新辅助治疗疗效的真实世界研究[J]. 中华临床医师杂志(电子版), 2023, 17(07): 765-770.
[12] 周婷, 孙培培, 张二明, 安欣华, 向平超. 北京市石景山区40岁及以上居民慢性阻塞性肺疾病诊断现状调查[J]. 中华临床医师杂志(电子版), 2023, 17(07): 790-797.
[13] 李变, 王莉娜, 桑田, 李珊, 杜雪燕, 李春华, 张兴云, 管巧, 王颖, 冯琪, 蒙景雯. 亚低温技术治疗缺氧缺血性脑病新生儿的临床分析[J]. 中华临床医师杂志(电子版), 2023, 17(06): 639-643.
[14] 戴俊, 李硕, 曹影, 汪守峰, 宋红毛, 蔡菁菁, 邵敏, 陈莉, 程雷, 怀德. 鼻内镜下改良高选择性翼管神经低温等离子消融术对中重度变应性鼻炎的效果研究[J]. 中华临床医师杂志(电子版), 2023, 17(06): 689-693.
[15] 符梅沙, 周玉华, 李慧, 薛春颜. 淋巴细胞免疫治疗对复发性流产患者外周血T淋巴细胞亚群分布与PD1/PD-L1表达的影响及意义[J]. 中华临床医师杂志(电子版), 2023, 17(06): 726-730.
阅读次数
全文


摘要