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中华肾病研究电子杂志 ›› 2023, Vol. 12 ›› Issue (05) : 291 -294. doi: 10.3877/cma.j.issn.2095-3216.2023.05.010

综述

"肠-皮肤轴"与尿毒症皮肤病变的关系研究进展
乔小梅, 孔凯丽, 方敬爱, 张晓东()   
  1. 030001 太原,山西医科大学第一临床医学院
    030001 太原,山西医科大学第一医院肾内科
  • 收稿日期:2022-08-25 出版日期:2023-10-28
  • 通信作者: 张晓东
  • 基金资助:
    山西省重点研发计划项目(201803D421063)

Research progress on the relationship between the "gut-skin axis" and the uremic skin lesions

Xiaomei Qiao, Kaili Kong, Jingai Fang, Xiaodong Zhang()   

  1. First Clinical School of Medicine, Shanxi Medical University
    Department of Nephrology, First Hospital of Shanxi Medical University; Taiyuan 030001, Shanxi Province, China
  • Received:2022-08-25 Published:2023-10-28
  • Corresponding author: Xiaodong Zhang
引用本文:

乔小梅, 孔凯丽, 方敬爱, 张晓东. "肠-皮肤轴"与尿毒症皮肤病变的关系研究进展[J/OL]. 中华肾病研究电子杂志, 2023, 12(05): 291-294.

Xiaomei Qiao, Kaili Kong, Jingai Fang, Xiaodong Zhang. Research progress on the relationship between the "gut-skin axis" and the uremic skin lesions[J/OL]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2023, 12(05): 291-294.

皮肤病变是尿毒症患者常见并发症之一,其发病机制尚未完全阐明。近期研究表明,肠道与皮肤病变有着紧密的关系,两者互相影响、相互作用,构成了"肠-皮肤轴"。本文综述了"肠-皮肤轴"与尿毒症皮肤病变关系的研究进展,以探讨其潜在的治疗手段。

The skin lesion is one of the common complications in patients with uremia, and their pathogenesis has not been fully elucidated. Recent studies have shown that there is a close relationship between the gut and skin lesions in that they both interact and influence each other, forming the "gut-skin axis" . This article reviewed the research progress on the relationship between the "gut-skin axis" and uremic skin lesions so as to explore the potential therapeutic methods.

图1 "肠-皮肤轴"在尿毒症皮肤病变中的机制
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