为进一步提高对糖尿病肾脏疾病的临床诊疗水平，规范糖尿病肾脏疾病西药以及中成药的临床应用，促进糖尿病肾脏疾病中西医结合精准诊疗的发展，中国中西医结合学会、中华中医药学会、中华医学会和解放军总医院牵头发起《糖尿病肾脏疾病中西医结合诊疗指南》的制订工作。 本文阐述了指南制订委员会的组建过程、临床问题的定义、数据收集与选择策略、证据的检索与筛选流程、推荐意见的确立、指南的外部审查、发布策略以及推广与执行措施。 本文旨在为指南的制订提供明确框架和技术支持，增强指南制订过程透明度，并为中西医结合领域其他诊疗指南的制订提供参考和借鉴。

To further enhance the clinical diagnosis and treatment level of diabetic kidney disease（DKD）， standardize the clinical application of Western and traditional Chinese medicines for DKD， and promote the development of precise diagnosis and treatment of DKD by integrated traditional Chinese and Western medicine， the Chinese Association of Integrative Medicine， the China Association of Chinese Medicine， the Chinese Medical Association， and the Chinese PLA General Hospital have taken the lead in initiating the formulation of guidelines for diagnosis and treatment of DKD with integrated traditional Chinese and Western medicine. This article elaborated on the formation process of the guideline development committee， the definition of clinical questions， data collection and selection strategies， the retrieval and screening process for evidence， the establishment of recommendations， external review of the guidelines，publication strategies， and promotion and implementation measures. The aim of this article was to provide a clear framework and technical support for the development of the guidelines， enhance the transparency of the guidelines development process， and offer references and insights for the formulation of other diagnostic and treatment guidelines in the field of integrated traditional Chinese and Western medicine.