| [1] |
Ba X, Ye T, Shang H, et al. Recent advances in nanomaterials for the treatment of acute kidney injury [J]. ACS Appl Mater Interfaces, 2024, 16(10): 12117-12148.
|
| [2] |
Hoste EA, Bagshaw SM, Bellomo R, et al. Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study [J]. Intensive Care Med, 2015, 41(8): 1411-1423.
|
| [3] |
Sato Y, Takahashi M, Yanagita M. Pathophysiology of AKI to CKD progression [J]. Semin Nephrol, 2020, 40(2), 206-215.
|
| [4] |
Qin W, Huang J, Zhang M, et al. Nanotechnology-based drug delivery systems for treating acute kidney injury [J]. ACS Biomater Sci Eng, 2024, 10(10): 6078-6096.
|
| [5] |
Roointan A, Xu R, Corrie S, et al. Nanotherapeutics in kidney disease: innovations, challenges, and future directions [J]. J Am Soc Nephrol, 2025, 36(3): 500-518.
|
| [6] |
Gholizadeh Z, Aliannezhadi M, Ghominejad M, et al. High specific surface area γ-Al2O3 nanoparticles synthesized by facile and low-cost co-precipitation method [J]. Sci Rep, 2023, 13(1): 6131.
|
| [7] |
Tomsa AM, Alexa AL, Junie ML, et al. Oxidative stress as a potential target in acute kidney injury [J]. PeerJ, 2019, 7: e8046.
|
| [8] |
Ostermann M, Liu K. Pathophysiology of AKI [J]. Best Pract Res Clin Anaesthesiol, 2017, 31(3): 305-314.
|
| [9] |
McCullough PA, Choi JP, Feghali GA, et al. Contrast-induced acute kidney injury [J]. J Am Coll Cardiol, 2016, 68(13): 1465-1473.
|
| [10] |
Quan Z, Wang S, Xie H, et al. ROS regulation in CNS disorder therapy: unveiling the dual roles of nanomedicine [J]. Small, 2025, 21(5): e2410031.
|
| [11] |
Ostermann M, Lumlertgul N, Jeong R, et al. Acute kidney injury [J]. Lancet, 2025, 405(10474): 241-256.
|
| [12] |
Li L, Shen Y, Tang Z, et al. Engineered nanodrug targeting oxidative stress for treatment of acute kidney injury [J]. Exploration (Beijing), 2023, 3(6): 20220148.
|
| [13] |
Ahmad A, Dempsey SK, Daneva Z, et al. Role of nitric oxide in the cardiovascular and renal systems [J]. Int J Mol Sci, 2018, 19(9): 2605.
|
| [14] |
Zhang X, Liang L, Wang F, et al. Irisin-encapsulated mitochondria-targeted biomimetic nanotherapeutics for alleviating acute kidney injury [J]. Adv Sci (Weinh), 2024, 11(38): e2402805.
|
| [15] |
Xiong J, Zhao J. Pyroptosis: the determinator of cell death and fate in acute kidney injury [J]. Kidney Dis (Basel), 2023, 10(2): 118-131.
|
| [16] |
Li N, Wang Y, Wang X, et al. Pathway network of pyroptosis and its potential inhibitors in acute kidney injury [J]. Pharmacol Res, 2022, 175: 106033.
|
| [17] |
Chen Z, Chen P, Zhu Y, et al. Cobalt oxyhydroxide nanozymes inhibit inflammation by targeting the NLRP3 inflammasome [J]. Adv Funct Mater, 2023, 33: 2370163.
|
| [18] |
Qin S, Liu C, Chen Y, et al. Cobaltosic oxide-polyethylene glycol-triphenylphosphine nanoparticles ameliorate the acute-to-chronic kidney disease transition by inducing BNIP3-mediated mitophagy [J]. Kidney Int, 2023, 103(5): 903-916.
|
| [19] |
Bai X, Kang J, Wei S, et al. A pH responsive nanocomposite for combination sonodynamic-immunotherapy with ferroptosis and calcium ion overload via SLC7A11/ACSL4/LPCAT3 pathway [J]. Exploration (Beijing), 2025, 5(1): 20240002.
|
| [20] |
Yu Y, Zhang L, Zhang D, et al. The role of ferroptosis in acute kidney injury: mechanisms and potential therapeutic targets [J]. Mol Cell Biochem, 2025, 480(2): 759-784.
|
| [21] |
Cao Y, Liu X, Guo C, et al. Biomimetic reactive oxygen/nitrogen nanoscavengers inhibit "ferroptosis storm" and modulate immune targeting for acute kidney injury [J]. J Control Release, 2025, 379: 59-76.
|
| [22] |
Li Y, Wang G, Wang T, et al. PEGylated gambogic acid nanoparticles enable efficient renal-targeted treatment of acute kidney injury [J]. Nano Lett, 2023, 23(12): 5641-5647.
|
| [23] |
Xu M, Qi Y, Liu G, et al. Size-dependent in vivo transport of nanoparticles: implications for delivery, targeting, and clearance [J]. ACS Nano, 2023, 17(21): 20825-20849.
|
| [24] |
Song J, Yu J, Prayogo GW, et al. Understanding kidney injury molecule 1: a novel immune factor in kidney pathophysiology [J]. Am J Transl Res, 2019, 11(3): 1219-1229.
|
| [25] |
Wajda J, Dumnicka P, Kolber W, et al. The marker of tubular injury, kidney injury molecule-1 (KIM-1), in acute kidney injury complicating acute pancreatitis: a preliminary study [J]. J Clin Med, 2020, 9(5): 1463.
|
| [26] |
Yu H. HDL and scavenger receptor class B type I (SRBI) [J]. Adv Exp Med Biol, 2022, 1377: 79-93.
|
| [27] |
He S, Li X, He Y, et al. High-density lipoprotein nanoparticles spontaneously target to damaged renal tubules and alleviate renal fibrosis by remodeling the fibrotic niches [J]. Nat Commun, 2025, 16(1): 1061.
|
| [28] |
Huang Z, Chun C, Li X. Kidney targeting peptide-modified biomimetic nanoplatforms for treatment of acute kidney injury [J]. J Control Release, 2023, 358: 368-381.
|
| [29] |
Sun M, Yang J, Fan Y, et al. Beyond extracellular vesicles: hybrid membrane nanovesicles as emerging advanced tools for biomedical applications [J]. Adv Sci (Weinh), 2023, 10(32): e2303617.
|
| [30] |
Li M, Fang F, Sun M, et al. Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine [J]. Theranostics, 2022, 12(11): 4879-4903.
|
| [31] |
Sun M, Li M, Hu M, et al. Fully bioactive nanodrugs: stem cell-derived exosomes engineered with biomacromolecules to treat CCl4- and extreme hepatectomy-induced acute liver failure [J]. ACS Nano, 2024, 18(50): 33907-33921.
|
| [32] |
Tang TT, Lv LL, Wang B, et al. Employing macrophage-derived microvesicle for kidney-targeted delivery of dexamethasone: an efficient therapeutic strategy against renal inflammation and fibrosis [J]. Theranostics, 2019, 9(16): 4740-4755.
|
| [33] |
Chen Q, Ding F, Zhang S, et al. Sequential therapy of acute kidney injury with a DNA nanodevice [J]. Nano Lett, 2021, 21(10): 4394-4402.
|
| [34] |
覃宛冰,刘庆华. 利用靶向纳米药物治疗急性肾损伤研究进展[J/OL]. 中华肾病研究电子杂志,2025, 14(3): 121-125.
|
| [35] |
Wang L, Zhou W, Chen H, et al. Barcoded screening identifies nanocarriers for protein delivery to kidney [J]. Nat Commun, 2025, 16(1): 899.
|
| [36] |
Gu XR, Tai YF, Liu Z, et al. Layer-by-layer assembly of renal-targeted polymeric nanoparticles for robust arginase-2 knockdown and contrast-induced acute kidney injury prevention [J]. Adv Healthc Mater, 2024, 13(20): e2304675.
|
| [37] |
Huang ZW, Shi Y, Zhai YY, et al. Hyaluronic acid coated bilirubin nanoparticles attenuate ischemia reperfusion-induced acute kidney injury [J]. J Control Release, 2021, 334: 275-289.
|
| [38] |
Liu D, Jin F, Shu G, et al. Enhanced efficiency of mitochondria-targeted peptide SS-31 for acute kidney injury by pH-responsive and AKI-kidney targeted nanopolyplexes [J]. Biomaterials, 2019, 211: 57-67.
|
| [39] |
Yu H, Jin F, Liu D, et al. ROS-responsive nano-drug delivery system combining mitochondria-targeting ceria nanoparticles with atorvastatin for acute kidney injury [J]. Theranostics, 2020, 10(5): 2342-2357.
|
| [40] |
Yang L, Dong S, Gai S, et al. Deep insight of design, mechanism, and cancer theranostic strategy of nanozymes [J]. Nanomicro Lett, 2023, 16(1): 28.
|
| [41] |
Lu Y, Cao C, Pan X, et al. Structure design mechanisms and inflammatory disease applications of nanozymes [J]. Nanoscale, 2022, 15(1): 14-40.
|
| [42] |
Singh S. Antioxidant nanozymes as next-generation therapeutics to free radical-mediated inflammatory diseases: a comprehensive review [J]. Int J Biol Macromol, 2024, 260(Pt 1): 129374.
|
| [43] |
Zhang F, Gao P, Qi M, et al. An artificial peroxynitrite-resistant superoxide dismutase for acute kidney injury alleviation [J]. Small, 2025, 26: e2503033.
|
| [44] |
Rezaei B, Yari P, Sanders SM, et al. Magnetic nanoparticles: a review on synthesis, characterization, functionalization, and biomedical applications [J]. Small, 2024, 20(5): e2304848.
|
| [45] |
Wu K, Su D, Liu J, et al. Magnetic nanoparticles in nanomedicine: a review of recent advances [J]. Nanotechnology, 2019, 30(50): 502003.
|
| [46] |
Wang J, Zha M, Zhao H, et al. Detection of kidney dysfunction through in vivo magnetic resonance imaging with renal-clearable gadolinium nanoprobes [J]. Anal Chem, 2022, 94(9): 4005-4011.
|
| [47] |
Zhou T, Dong Y, Wang X, et al. Highly sensitive early diagnosis of kidney damage using renal clearable zwitterion-coated ferrite nanoprobe via magnetic resonance imaging in vivo [J]. Adv Healthc Mater, 2024, 13(12): e2304577.
|
| [48] |
Sharma I, Sharaf MG, Pawar A, et al. Hemocompatibility of albumin-modified magnetic nanoparticles [J]. Int J Mol Sci, 2024, 25(22): 11975.
|
| [49] |
Liu L, Xu Q, Zhang L, et al. Fe3O4 magnetic nanoparticles ameliorate albumin-induced tubulointerstitial fibrosis by autophagy related to Rab7 [J]. Colloids Surf B Biointerfaces, 2021, 198: 111470.
|
| [50] |
Li J, Duan Q, Wei X, et al. Kidney-targeted nanoparticles loaded with the natural antioxidant rosmarinic acid for acute kidney injury treatment [J]. Small, 2022, 18(48): e2204388.
|
| [51] |
Lei Y, Wu Y, Zhuang WR, et al. NAD+ biosynthesis and mitochondrial repair in acute kidney injury via ultrasound-responsive thylakoid-integrating liposomes [J]. Nat Biomed Eng, 2025, 9(10): 1740-1757.
|
| [52] |
Ding L, Liang X, Ma J, et al. Sono-triggered biomimetically nanoantibiotics mediate precise sequential therapy of MRSA-induced lung infection [J]. Adv Mater, 2024, 36(46): e2403612.
|
| [53] |
Xu Y, Zhang Q, Chen R, et al. NIR-II photoacoustic-active DNA origami nanoantenna for early diagnosis and smart therapy of acute kidney injury [J]. J Am Chem Soc, 2022, 144(51): 23522-23533.
|
| [54] |
Zeng F, Nijiati S, Liu Y, et al. Ferroptosis MRI for early detection of anticancer drug-induced acute cardiac/kidney injuries [J]. Sci Adv, 2023, 9(10): eadd8539.
|
| [55] |
Sun J, Han Y, Dong J, et al. Melanin/melanin-like nanoparticles: as a naturally active platform for imaging-guided disease therapy [J]. Mater Today Bio, 2023, 23: 100894.
|
| [56] |
Zhao X, Sun J, Dong J, et al. An auto-photoacoustic melanin-based drug delivery nano-platform for self-monitoring of acute kidney injury therapy via a triple-collaborative strategy [J]. Acta Biomater, 2022, 147: 327-341.
|
| [57] |
Fang F, Wang S, Song Y, et al. Continuous spatiotemporal therapy of a full-API nanodrug via multi-step tandem endogenous biosynthesis [J]. Nat Commun, 2023, 14(1): 1660.
|
| [58] |
Zhang C, Zhao D, Fang F, et al. Quintuple free-radical therapy: an ultralong-retention FAND for NIR-involved multiple site-action hypoxic tumor therapy [J]. Adv Funct Mater, 2024, 34(37): 2401840.
|