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中华肾病研究电子杂志 ›› 2025, Vol. 14 ›› Issue (05) : 294 -296. doi: 10.3877/cma.j.issn.2095-3216.2025.05.008

病例报告

膜性肾病合并抗肾小球基底膜病1例并文献复习
张珊珊1, 孙晓伟2, 吴杰2,(), 王小龙2, 陈仆2, 陈婧婧2, 尹忠2, 白圆圆2, 蔡广研2   
  1. 1256200 邹平市人民医院
    2100853 北京,解放军总医院肾脏病医学部,肾脏疾病全国重点实验室,国家慢性肾病临床医学研究中心,重症肾脏疾病器械与中西医药物研发北京市重点实验室、数智中医泛血管疾病防治北京市重点实验室、国家中医药管理局高水平中医药重点学科(zyyzdxk-2023310)
  • 收稿日期:2024-12-24 出版日期:2025-10-28
  • 通信作者: 吴杰

Membranous nephropathy complicated with anti-glomerular basement membrane disease: a case and literature review

Shanshan Zhang, Xiaowei Sun, Jie Wu()   

  • Received:2024-12-24 Published:2025-10-28
  • Corresponding author: Jie Wu
引用本文:

张珊珊, 孙晓伟, 吴杰, 王小龙, 陈仆, 陈婧婧, 尹忠, 白圆圆, 蔡广研. 膜性肾病合并抗肾小球基底膜病1例并文献复习[J/OL]. 中华肾病研究电子杂志, 2025, 14(05): 294-296.

Shanshan Zhang, Xiaowei Sun, Jie Wu. Membranous nephropathy complicated with anti-glomerular basement membrane disease: a case and literature review[J/OL]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2025, 14(05): 294-296.

图1 肾脏活检病理组织学注:A、B:PAS染色显示肾小球未见新月体,系膜细胞未见明显增殖,系膜区无增宽,内皮细胞未见明显增殖,毛细血管裆开放良好;C、D:PAM染色显示肾小球基底膜稍增厚,上皮下可见少量嗜复红物质沉积。未见钉突及双轨;E、F:免疫荧光显示IgG (+2)、C3(+)、IgG1(+)、IgG4(+)沿毛细血管祥颗粒样沉积;G、H:电镜观察显示基底膜稍有增厚,足突细胞节段融合,上皮下见电子致密物沉积
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