The most common complications of idiopathic membranous nephropathy (IMN) are vein thrombosis and embolism, which can cause varying degrees of damage to the body, aggravate the patients′ disease progression, exacerbate the prognosis, and even cause death. But so far, there have been neither reliable laboratory indexes nor uniform standards or measures for guiding clinical diagnosis and treatment. According to the latest domestic and foreign research progress, we explored the clinical intervention to the vein thrombosis or embolism complication in IMN from the perspective of prevention and treatment, and overviewed the monitoring indexes during the treatment process for the venous thrombosis or embolism complication in IMN.