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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2016, Vol. 05 ›› Issue (02): 61-64. doi: 10.3877/cma.j.issn.2095-3216.2016.02.004

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Progress in diagnosis and treatment of hemolytic uremic syndrome

Xiaorong Liu1,()   

  1. 1. Department of Nephrology, Beijing Children′s Hospital Affiliated to Capital University of Medical Sciences, Beijing Key Laboratory for Children′s Chronic Kidney Diseases and Blood Purification, Beijing 100045, China
  • Received:2016-03-01 Online:2016-04-28 Published:2016-04-28
  • Contact: Xiaorong Liu
  • About author:
    Corresponding author: Liu Xiaorong, Email:

Abstract:

Hemolytic uremic syndrome (HUS) is a thrombotic microvascular disease, characterized by microvascular hemolytic anemia (red blood cell debris can be found), thrombocytopenia, and renal function damage. Micro thrombus mainly distributed in the kidney. Key factors for the pathogenesis includes infection, toxins, anti-endothelial cell antibodies, and drugs. In recent years, new recognition has been made for the causes and pathogenesis of HUS, and plasma infusion and plasmapheresis have been the most effective methods for treatment of HUS, greatly improving the survival rate of HUS patients.

Key words: Hemolytic uremic syndrome, Child, Diagnosis, Treatment

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