Susceptibility to kidney injury in premature / low birth weight infants and its mechanism

doi:10.3877/cma.j.issn.2095-3216.2017.02.009

Abstract

Abstract:

Many factors could affect the development of fetal kidneys, such as maternal nutritional status, health, medication, and so on. Premature and low birth weight infants (LBWI) have immature glomeruli and tubules as well as reduced nephrons, and are prone to renal diseases during their minority, including acute renal injury, focal segmental glomerular sclerosis, etc. In addition, premature infants and LBWI will be susceptible to hypertension and diabetes during their adult period, which may lead to kidney injury. Revealing the pathogenesis and development mechanism of kidney injury in premature infants and LBWI will be helpful for early intervention and delaying the progression of kidney diseases.

Key words: Premature, Low birth weight, Kidney disease, Hypertension, Diabetes mellitus

Jing Cao, Yuansheng Xie. Susceptibility to kidney injury in premature / low birth weight infants and its mechanism[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2017, 06(02): 88-91.

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