Acute kidney disease (AKD) describes acute or subacute renal damage and/or loss of kidney function between 7 and 90 days after AKI initiation. It is an important period of transition after AKI. The treatment of this period is essential for the eventual prognosis of AKI. Recently, ADQI working group provided consensus on the definition, stages, and treatment and prevention strategy of AKD. This article summarized the current clinical practice strategy for AKD. The effective preventive measures for AKD includes actively screening susceptible factors, identifying high-risk groups, avoiding use of nephrotoxic drugs, keeping enough renal perfusion, and maintaining the stable internal environment. The other measures for AKD were also emphasized, including follow-up requirements, drug adjustment strategy, renal replacement therapy, and treatment for primary diseases. Increasing awareness of AKD plus active intervention will promote the recovery of progressive AKI, and reduce the occurrence and progression of CKD.