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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2018, Vol. 07 ›› Issue (05): 234-237. doi: 10.3877/cma.j.issn.2095-3216.2018.05.010

Special Issue:

• Review • Previous Articles     Next Articles

Application status of rituximab in refractory nephrotic syndrome

Zhongxin Jin1, Yufeng Qiao2,()   

  1. 1. Shanxi Medical University; Taiyuan 030001, Shanxi Province, China
    2. Second Hospital of Shanxi Medical University, Kidney Disease Institute of Shanxi Province; Taiyuan 030001, Shanxi Province, China
  • Received:2018-04-12 Online:2018-10-28 Published:2018-10-28
  • Contact: Yufeng Qiao
  • About author:
    Corresponding author: Qiao Yufeng, Email:

Abstract:

Idiopathic nephrotic syndrome (INS) is a common glomerular disease in children and adults. Glucocorticoid is the basic drug for INS treatment. Most patients with idiopathic refractory nephrotic syndrome (IRNS) need to use other immunosuppressants or cytotoxic drugs on the basis of glucocorticoids. In recent years, some scholars have used rituximab (RTX) to treat IRNS and achieved good results. This article reviewed the pathogenesis of IRNS and the application of RTX in different pathological types.

Key words: Rituximab, Refractory nephrotic syndrome

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