Advances in research on the mechanism of microRNA in diabetic nephropathy

doi:10.3877/cma.j.issn.2095-3216.2019.03.008

Abstract

Abstract:

Diabetic nephropathy (DN) is one of the important microvascular complications of diabetes. Currently, there is a lack of highly sensitive and specific biodiagnostic markers for non-invasive diagnosis of DN. MicroRNAs (miRNAs) are widely present in organisms and play a key role in a variety of physiological and pathological processes, participating in the pathogenesis of DN. The discovery of blood- and urine-specific miRNAs in patients with DN provides a new direction for the search for diagnostic markers of DN, and will play an important role in the diagnosis of DN and the assessment of disease severity.

Key words: Diabetic nephropathy, MicroRNA, Mechanism

Tingting Jiao, Qiuxia Han, Dong Zhang, Youcai Zhang, Li Tang, Guangyan Cai, Xiangmei Chen, Hanyu Zhu. Advances in research on the mechanism of microRNA in diabetic nephropathy[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2019, 08(03): 138-141.

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