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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2024, Vol. 13 ›› Issue (02): 106-112. doi: 10.3877/cma.j.issn.2095-3216.2024.02.009

• Review • Previous Articles    

Research progress on the transition from acute kidney injury to chronic kidney disease

Yinan Zhang1, Guozhen Zhu2,()   

  1. 1. Shanxi Medical University
    2. Department of Nephrology, Second Hospital of Shanxi Medical University; Taiyuan 030001, Shanxi Province, China
  • Received:2023-08-24 Online:2024-04-28 Published:2024-05-13
  • Contact: Guozhen Zhu

Abstract:

Although some patients with acute kidney injury (AKI) got clinical recovery, they still experienced renal tissue fibrosis due to changes in renal structure and maladaptive repair, leading to progression to chronic kidney disease (CKD) and even end-stage renal disease (ESRD). Therefore, early identification and intervention of the AKI-to-CKD transition is crucial. This article reviewed the research progress on the risk factors, transition mechanisms, biomarkers, and intervention measures of the AKI-to-CKD transition.

Key words: Acute kidney injury, Chronic kidney disease, Transition, Mechanisms, Biomarkers, Intervention

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