Renal replacement therapy (RRT) is widely used in the intensive care unit (ICU), but its application in patients with acute kidney injury (AKI) still lacks unified standards. In November 2024, the French Society of Intensive Care Medicine, in collaboration with the French Pediatric Critical Care and Emergency Group, published an evidence-based guideline for both adult and pediatric patients with AKI. This guideline systematically updates the management strategies for RRT in the ICU. It emphasizes the deferral of RRT initiation in the absence of emergent indications, the equivalence of outcomes across different RRT modalities, and the feasibility of peritoneal dialysis under resource constraints, while specifying the initiation indications for pediatric patients with hyperammonemia. At the implementation level, it proposes a conservative dosing regimen for adults and an individualized approach for pediatric patients. Furthermore, it does not recommend heparin locking for patients at high risk of bleeding, highlighting the importance of blood volume management and daily weaning assessments. This article reviews and interprets the main recommendations of the guideline, and discusses their implications for the standardized management of RRT in China.