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中华肾病研究电子杂志 ›› 2018, Vol. 07 ›› Issue (01) : 39 -43. doi: 10.3877/cma.j.issn.2095-3216.2018.01.009

所属专题: 文献

综述

老年维持性血液透析患者死亡危险因素研究进展
宋玉环1, 蔡广研2,(), 肖跃飞3, 陈香美2   
  1. 1. 100853 北京,解放军总医院肾脏病科、解放军肾脏病研究所、肾脏疾病国家重点实验室、国家慢性肾病临床医学研究中心;100049 北京大学航天临床医学院、航天中心医院肾脏内科
    2. 100853 北京,解放军总医院肾脏病科、解放军肾脏病研究所、肾脏疾病国家重点实验室、国家慢性肾病临床医学研究中心
    3. 100049 北京大学航天临床医学院、航天中心医院肾脏内科
  • 收稿日期:2017-11-16 出版日期:2018-02-28
  • 通信作者: 蔡广研
  • 基金资助:
    国家科技支撑计划课题(2015BAI12B06, 2011BAI10B03)

Progress of research on mortality risk factors in elderly patients undergoing maintenance hemodialysis

Yuhuan Song1, Guangyan Cai2,(), Yuefei Xiao3, Xiangmei Chen2   

  1. 1. Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing 100853; Department of Nephrology, Aerospace Central Hospital, Peking University School of Aerospace Clinical Medicine, Beijing 100049, China
    2. Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing 100853
    3. Department of Nephrology, Aerospace Central Hospital, Peking University School of Aerospace Clinical Medicine, Beijing 100049, China
  • Received:2017-11-16 Published:2018-02-28
  • Corresponding author: Guangyan Cai
  • About author:
    Corresponding author: Cai Guangyan, Email:
引用本文:

宋玉环, 蔡广研, 肖跃飞, 陈香美. 老年维持性血液透析患者死亡危险因素研究进展[J/OL]. 中华肾病研究电子杂志, 2018, 07(01): 39-43.

Yuhuan Song, Guangyan Cai, Yuefei Xiao, Xiangmei Chen. Progress of research on mortality risk factors in elderly patients undergoing maintenance hemodialysis[J/OL]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2018, 07(01): 39-43.

随着人均寿命的延长、代谢性疾病和动脉粥样硬化发病率的不断上升和血液净化技术的不断改进,老年维持性血液透析(MHD)患者数量逐年增加。由于老年患者独特的生理特点及合并症的增加,老年MHD患者的生活质量及生存率均不及中青年患者,死亡率仍较高。常见死亡原因有心脑血管疾病、感染、消化道出血及肿瘤等。诸多死亡危险因素中包括了年龄、合并糖尿病、高血压、营养不良、血管通路类型及心理疾患等。本文系统综述了老年血液透析患者的死亡原因及相关危险因素的研究进展,为临床进行前瞻干预提供依据。

With the increase of average life expectancy of humanity, the rising of incidences of metabolic diseases and atherosclerosis, and the continuous improvement of blood purification technology, the number of elderly patients with maintenance hemodialysis (MHD) increases year by year. Due to the unique physiological characteristics and the increase of comorbidities in elderly patients, the elderly MHD patients have lower quality of life and lower survival rate, but higher mortality rate than the young and middle-aged patients. The common causes of death include cardiovascular and cerebrovascular diseases, infections, gastrointestinal bleeding, and tumors. Many death risk factors include age, diabetes mellitus, hypertension, malnutrition, types of vascular access, and mental disorders. This article systematically elaborated the research progress of the causes of death and related risk factors in elderly hemodialysis patients, so as to provide evidence for clinical prospective interventions.

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