慢性肾脏病(CKD)孕妇的管理是肾脏科和产科医师共同的难题，近年随着医学的发展、对强化透析的认识、多学科协同管理模式的支持，CKD患者的妊娠结局越来越好。本文主要概述了CKD与妊娠的相互影响、影响CKD患者妊娠结局的危险因素、妊娠时机、肾脏评价指标及调整用药等方面的共识及进展，阐述妊娠前肾功能分期、原发病、血压和尿蛋白水平对妊娠结局的影响，为保障CKD女性的肾脏及下一代健康，预防和减少不良妊娠结局的发生提供指导。

Management of pregnant women with chronic kidney disease (CKD) is a common problem for both nephrologists and obstetricians. With the recent development of medicine, implementation of intensive dialysis, and support of multidisciplinary cooperative management, the pregnancy outcome of CKD patients is getting better and better. This article mainly summarized consensus and progress in the mutual influence of CKD and pregnancy, the risk factors affecting the pregnancy outcome of CKD patients, the timing of pregnancy, kidney evaluation indicators, and adjustments in drug use. The authors also explained the effects of pre-pregnancy renal function staging, primary diseases, blood pressure, and urinary protein levels on pregnancy outcomes, so as to provide guidance for protecting the kidneys of women with CKD and the health of next generation, as well as preventing and reducing adverse outcomes of pregnancy.