| [1] |
Perschinka F，Peer A，Joannidis M. Artificial intelligence and acute kidney injury [J]. Med Klin Intensivmed Notfmed，2024，119（3）：199-207.
|
| [2] |
Bejoy J，Qian ES，Woodard LE. Tissue culture models of AKI：from tubule cells to human kidney organoids [J]. J Am Soc Nephrol，2022，33（3）：487-501.
|
| [3] |
Horne KL，Viramontes-Hörner D，Packington R，et al. A comprehensive description of kidney disease progression after acute kidney injury from a prospective，parallel-group cohort study [J]. Kidney Int，2023，104（6）：1185-1193.
|
| [4] |
Wang Z，Zhang C. From AKI to CKD： maladaptive repair and the underlying mechanisms [J]. Int J Mol Sci，2022，23（18）：10880.
|
| [5] |
Zhao L，Hao Y，Tang S，et al. Energy metabolic reprogramming regulates programmed cell death of renal tubular epithelial cells and might serve as a new therapeutic target for acute kidney injury [J]. Front Cell Dev Biol，2023，11：1276217.
|
| [6] |
Ling ZN，Jiang YF，Ru JN，et al. Amino acid metabolism in health and disease [J]. Signal Transduct Target Ther，2023，8（1）：345.
|
| [7] |
Patschan D，Patschan S，Matyukhin I，et al. Metabolomics in acute kidney injury： the experimental perspective [J]. J Clin Med Res，2023，15（6）：283-291.
|
| [8] |
Dai X，Shen L. Advances and trends in omics technology development [J]. Front Med （Lausanne），2022，9：911861.
|
| [9] |
Lacy P. Metabolomics of sepsis-induced acute lung injury：a new approach for biomarkers [J]. Am J Physiol Lung Cell Mol Physiol，2011，300（1）： L1-L3.
|
| [10] |
林惠，乔晞. 表观遗传修饰在急性肾损伤向慢性肾脏病转变中的作用[J]. 中华肾脏病杂志，2020，36（2）：171-176.
|
| [11] |
Moreno-Gordaliza E，González-Nicolás Má，Lázaro A，et al.Untargeted metabolomics analysis of serum and urine unveils the protective effect of cilastatin on altered metabolic pathways during cisplatin-induced acute kidney injury [J]. Biochem Pharmacol，2024，227：116435.
|
| [12] |
Vašková J，Kocan L，Vaško L，et al. Glutathione-related enzymes and proteins：a review [J]. Molecules，2023，28（3）：1447.
|
| [13] |
Ferreira MJ，Rodrigues TA，Pedrosa AG，et al. Glutathione and peroxisome redox homeostasis [J]. Redox Biol，2023，67：102917.
|
| [14] |
Guo R，Duan J，Pan S，et al. The road from AKI to CKD：molecular mechanisms and therapeutic targets of ferroptosis [J].Cell Death Dis，2023，14（7）：426.
|
| [15] |
Ide S，Kobayashi Y，Ide K，et al. Ferroptotic stress promotes the accumulation of proinflammatory proximal tubular cells in maladaptive renal repair [J]. Elife，2021，10： e68603.
|
| [16] |
王小巍，张红艳，刘锐，等. 谷胱甘肽的研究进展[J]. 中国药剂学杂志（网络版），2019，17（4）：141-148.
|
| [17] |
Costa I，Barbosa DJ，Benfeito S，et al. Molecular mechanisms of ferroptosis and their involvement in brain diseases [ J].Pharmacol Ther，2023，244：108373.
|
| [18] |
Lin W，Wang C，Liu G，et al. SLC7A11/xCT in cancer：biological functions and therapeutic implications [J]. Am J Cancer Res，2020，10（10）：3106-3126.
|
| [19] |
Ding C，Ding X，Zheng J，et al. MiR-182-5p and miR-378a-3p regulate ferroptosis in I/R-induced renal injury [J]. Cell Death Dis，2020，11（10）：929.
|
| [20] |
Pei J，Pan X，Wei G，et al. Research progress of glutathione peroxidase family （GPX） in redoxidation [J]. Front Pharmacol，2023，14：1147414.
|
| [21] |
Ni L，Yuan C，Wu X. Targeting ferroptosis in acute kidney injury [J]. Cell Death Dis，2022，13（2）：182.
|
| [22] |
Caldwell RW，Rodriguez PC，Toque HA，et al. Arginase： a multifaceted enzyme important in health and disease [J]. Physiol Rev，2018，98（2）：641-665.
|
| [23] |
Maric S，Restin T，Muff JL，et al. Citrulline，biomarker of enterocyte functional mass and dietary supplement. Metabolism，transport，and current evidence for clinical use [J]. Nutrients，2021，13（8）：2794.
|
| [24] |
Hara M，Torisu K，Tomita K，et al. Arginase 2 is a mediator of ischemia-reperfusion injury in the kidney through regulation of nitrosative stress [J]. Kidney Int，2020，98（3）：673-685.
|
| [25] |
Zahedi K，Barone S，Soleimani M. Polyamine catabolism in acute kidney injury [J]. Int J Mol Sci，2019，20（19）：4790.
|
| [26] |
Zahedi K，Barone S，Brooks M，et al. Polyamine catabolism and its role in renal injury and fibrosis in mice subjected to repeated lowdose cisplatin treatment [J]. Biomedicines，2024，12（3）：640.
|
| [27] |
Bahri S，Zerrouk N，Aussel C，et al. Citrulline： from metabolism to therapeutic use [J]. Nutrition，2013，29（3）：479-484.
|
| [28] |
Rashid J，Kumar SS，Job KM，et al. Therapeutic potential of citrulline as an arginine supplement： a clinical pharmacology review [J]. Paediatr Drugs，2020，22（3）：279-293.
|
| [29] |
Wijnands KA，Castermans TM，Hommen MP，et al. Arginine and citrulline and the immune response in sepsis[J]. Nutrients，2015，7（3）：1426-1463.
|
| [30] |
Taguchi K，Sugahara S，Elias BC，et al. IL-22 is secreted by proximal tubule cells and regulates DNA damage response and cell death in acute kidney injury [J]. Kidney Int，2024，105（1）：99-114.
|
| [31] |
Tanuseputero SA，Lin MT，Yeh SL，et al. Intravenous arginine administration downregulates NLRP3 inflammasome activity and attenuates acute kidney injury in mice with polymicrobial sepsis[J]. Mediators Inflamm，2020，2020：3201635.
|
| [32] |
Zhou LY，Liu K，Yin WJ，et al. Arginase 2 mediates contrastinduced acute kidney injury via facilitating nitrosative stress in tubular cells [J]. Redox Biol，2023，67：102929.
|
| [33] |
Liang M，Wang Z，Li H，et al. l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway [J]. Food Chem Toxicol，2018，115：315-328.
|
| [34] |
Caldwell RW，Rodriguez PC，Toque HA，et al. Arginase： a multifaceted enzyme important in health and disease [J]. Physiol Rev，2018，98（2）：641-665.
|
| [35] |
赵晓庆，乔晞. 急性肾损伤向慢性肾脏病转变的机制研究进展[J]. 生命科学，2019，31（3）：279-283.
|
| [36] |
Yu J，Yu C，Bayliss G，et al. Protein arginine methyltransferases in renal development，injury，repair，and fibrosis [J]. Front Pharmacol，2023，14：1123415.
|
| [37] |
Nakayama Y，Ueda S，Yamagishi S，et al. Asymmetric dimethylarginine accumulates in the kidney during ischemia/reperfusion injury [J]. Kidney Int，2014，85（3）：570-857.
|
| [38] |
Cheng HH，Kuo CC，Yan JL，et al. Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan[J]. Proc Natl Acad Sci USA，2012，109（33）：13231-13236.
|
| [39] |
Zheng X，Zhang A，Binnie M，et al. Kynurenine 3-monooxygenase is a critical regulator of renal ischemia-reperfusion injury [J]. Exp Mol Med，2019，51（2）：1-14.
|
| [40] |
Krupa A，Krupa MM，Pawlak K. Indoleamine 2，3 dioxygenase 1-the potential link between the innate immunity and the ischemia-reperfusion-induced acute kidney injury? [J] Int J Mol Sci，2022，23（11）：6176.
|
| [41] |
Piret SE，Guo Y，Attallah AA，et al. Krüppel-like factor 6-mediated loss of BCAA catabolism contributes to kidney injury in mice and humans [J]. Proc Natl Acad Sci USA，2021，118（23）： e2024414118.
|