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中华肾病研究电子杂志 ›› 2022, Vol. 11 ›› Issue (06) : 301 -306. doi: 10.3877/cma.j.issn.2095-3216.2022.06.001

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肾素-血管紧张素-醛固酮系统抑制剂治疗伴有心力衰竭的慢性肾脏病
孙雪峰1,()   
  1. 1. 100853 北京,解放军总医院第一医学中心肾脏病医学部、解放军肾脏病研究所、肾脏疾病国家重点实验室、国家慢性肾病临床医学研究中心、肾脏疾病研究北京市重点实验室
  • 收稿日期:2022-06-21 出版日期:2022-12-28
  • 通信作者: 孙雪峰
  • 基金资助:
    国家自然科学基金面上项目(81870463,92049103)

RAAS inhibitors in the treatment of patients with chronic kidney disease accompanied by heart failure

Xuefeng Sun1,()   

  1. 1. Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Beijing 100853, China
  • Received:2022-06-21 Published:2022-12-28
  • Corresponding author: Xuefeng Sun
引用本文:

孙雪峰. 肾素-血管紧张素-醛固酮系统抑制剂治疗伴有心力衰竭的慢性肾脏病[J]. 中华肾病研究电子杂志, 2022, 11(06): 301-306.

Xuefeng Sun. RAAS inhibitors in the treatment of patients with chronic kidney disease accompanied by heart failure[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2022, 11(06): 301-306.

肾素-血管紧张素-醛固酮系统(RAAS)抑制剂是治疗慢性肾脏病和心力衰竭的基础用药,但应用于伴有心力衰竭的慢性肾脏病患者尚存问题。本文在介绍不同种类RAAS抑制剂的药理作用基础上,基于循证证据论述了RAAS抑制剂治疗慢性肾脏病和心力衰竭的疗效以及联合应用的问题,旨在为临床医生合理应用RAAS抑制剂治疗伴有心力衰竭的慢性肾脏病,提供借鉴和参考。

Renin angiotensin aldosterone system (RAAS) inhibitors are the basic drugs for the treatment of chronic kidney disease and heart failure, but there are still problems in the application of RAAS inhibitors for patients with chronic kidney disease accompanied by heart failure. Based on evidence-based medicine, this paper introduced the pharmacological effects of different kinds of RAAS inhibitors, and discussed the efficacy of RAAS inhibitors in the treatment of chronic kidney disease and heart failure, as well as problems in the combined application of RAAS inhibitors, so as to provide reference for clinicians to reasonably use RAAS inhibitors in the treatment of patients with chronic kidney disease accompanied by heart failure.

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