Development of stem cell therapy in kidney disease

doi:10.3877/cma.j.issn.2095-3216.2012.02.011

Abstract

Abstract:

The incidence of chronic kidney disease (CKD) and acute kidney injury(AKI) are increasing gradually in each year, which becomes life threatening diseases in these years because of lack of effective therapy. In recent years, stem cells and regenerative medicine may provide additional regenerative options for kidney disease. Such new treatments might involve induction of repair using endogenous or exogenous stem cells or the reprogramming of the organ to reinitiate development. This review addresses the current state of understanding with respect to exogenous stem cell therapy in the biology of normal renal repair in response to damage. It also summarizes the remaining problems and provides clues of stem cell therapy in kidney disease.

Key words: Kidney disease, Treatment, Stem cells

Jie HU, Xiang-mei CHEN. Development of stem cell therapy in kidney disease[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2012, 01(02): 116-118.

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