The structure, metabolism, receptors of retinoic acid and its relationship with organ development

doi:10.3877/cma.j.issn.2095-3216.2015.05.008

Abstract

Abstract:

Vitamin A is a kind of essential fat-soluble vitamin in human body. Retinoic acid (RA), the main metabolite of vitamin A, plays an important role in the formation and differentiation of organs and the proliferation and apoptosis of tissue or cells. The deficiency or excess intake of RA will cause abnormal development of tissues and organs. The present paper has reviewed the molecular structure, metabolism process, receptors of RA, and the interaction between RA and organ development, in order to improve recognization of the relationship between RA and the development of organs.

Key words: Vitamin A, Retinoic acid, Retinoic acid receptor, Organ development

Yan Qi, Yuansheng Xie. The structure, metabolism, receptors of retinoic acid and its relationship with organ development[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2015, 04(05): 257-260.

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