Advances in diagnosis and treatment of uremic tumoral calcinosis

doi:10.3877/cma.j.issn.2095-3216.2022.03.007

Abstract

Abstract:

Uremic tumoral calcinosis is a rare complication in patients with end-stage renal disease. It is characterized by disturbance of calcium and phosphorus metabolism and deposition of calcium in soft tissues around joints, which can seriously threaten the quality of life and even life of patients. Due to its extremely low incidence, the clinical understanding of it is often insufficient, and there is currently no unified diagnosis and treatment standard, making it easily misdiagnosed and mistreated. In order to improve clinicians′ understanding of the disease, and to achieve early diagnosis and timely treatment as much as possible, this article reviewed the progress in the diagnosis and treatment of uremic tumoral calcinosis.

Key words: Uremia, Tumoral calcinosis, Diagnosis, Treatment

Yan Li, Santao Ou. Advances in diagnosis and treatment of uremic tumoral calcinosis[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2022, 11(03): 152-155.

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References 35

[1]	石磊，田蓉. 99Tcm-MDP全身骨显像发现肿瘤样钙质沉着症1例[J]. 标记免疫分析与临床，2018, 25(10): 1574-1576.
[2]	Yano H, Kinjo M. Tumoral calcinosis [J]. Cleve Clin J Med, 2021, 88(4): 208-209.
[3]	Chu HY, Chu P, Lin YF, et al. Uremic tumoral calcinosis in patients on peritoneal dialysis: clinical, radiologic, and laboratory features [J]. Perit Dial Int, 2011, 31(4): 430-439.
[4]	Zhou H, Yang M, Zou Y. Uraemic tumoral calcinosis in a peritoneal dialysis patient [J]. Intern Med J, 2018, 48(12): 1544-1546.
[5]	Azami A, Mohebbipour Loron A, Anari H, et al. Case report: a report of a rare case tumoral calcinosis syndrome in a patient afflicted with psoriatic arthritis [J]. Arch Osteoporos, 2020, 15(1): 106-106.
[6]	Inclan A, Leon P, Camejo MG. Tumoral calcinosis [J]. JAMA, 1943, 121(7): 490-495.
[7]	Smack D, Norton SA, Fitzpatrick JE. Proposal for a pathogenesis-based classification of tumoral calcinosis [J]. Int J Dermatol, 1996, 35(4): 265-271.
[8]	Lafferty FW, Reynolds ES, Pearson OH. Tumoral calcinosis: a metabolic disease of obscure etiology [J]. Am J Med, 1965, 38: 105-118.
[9]	Ke G, Li S, Cui Y, et al. Treatment of uremic tumoral calcinosis in maintenance hemodialysis patients [J]. Blood Purif, 2020, 49(6): 658-664.
[10]	熊敏，王晶，李旭东，等. 尿毒症肿瘤样钙质沉着症10例临床分析[J]. 中华内科杂志，2020, 59(11): 860-865.
[11]	Rui G, Tatsuya K, Tetsushi K, et al. Tumoral calcinosis in the cervical spine: a case report and review of the literature [J]. J Med Case Rep, 2017, 11(1): 304-304.
[12]	Wang J, Zeng M, Yang G, et al. Effects of parathyroidectomy on tumoral calcinosis in uremic patients with secondary hyperparathyroidism [J]. BMC Surg, 2019, 19(1): 133-133.
[13]	Fatehi M, Ahuja CS, Wang S, et al. Uremic tumoral calcinosis in the cervical spine: case report [J]. J Neurosurg Spine, 2016, 25(1): 26-30.
[14]	Kendal JK, Evaniew N, Swamy G. Uremic tumoral calcinosis of the cervical spine [J]. CMAJ, 2020, 192(39): E1133.
[15]	Aristizabal-Alzate A, Nieto-Rios JF, Trujillo-Agudelo D, et al. Uremic tumoral calcinosis with atypical manifestation. Case report [J]. Nefrologia (Engl Ed), 2020, Epub ahead of print.
[16]	Li H, Bai Y, An N, et al. A case report of scrotal tumoral calcinosis in a patient on maintenance hemodialysis [J]. Urol Case Rep, 2020, 33: 101270.
[17]	An J, Khalidi N. Esophageal obstruction secondary to massive tumoral calcinosis [J]. J Rheumatol, 2021, 48(5): 786-786.
[18]	赵雪梅，杜奕，杨萍，等. 肿瘤样钙质沉着症影像学特点表现[J]. 宁夏医科大学学报，2020, 42(6): 627-630.
[19]	Goossens J, Courbebaisse M, Caudron E, et al. Efficacy of intralesional sodium thiosulfate injections for disabling tumoral calcinosis: two cases [J]. Semin Arthritis Rheum, 2017, 47(3): 451-455.
[20]	Olsen KM, Chew FS. Tumoral calcinosis: pearls, polemics, and alternative possibilities [J]. Radiographics, 2006, 26(3): 871-885.
[21]	Lai LA, Hsiao MY, Wu CH, et al. Big gain, no pain: tumoral calcinosis [J]. Am J Med, 2018, 131(1): 45-47.
[22]	Zuo QY, Cao X, Liu BY, et al. Clinical and genetic analysis of idiopathic normophosphatemic tumoral calcinosis in 19 patients [J]. J Endocrinol Invest, 2020, 43(2): 173-183.
[23]	Dierickx J, Vanhoenacker F. Idiopathic tumoral calcinosis [J]. J Belg Soc Radiol, 2021, 105(1): 6.
[24]	Chi D, Kamochi H, Sunaga A, et al. Tumoral calcinosis: a giant tumoral mass in the shoulder joint of a dialysis patient [J]. Plast Reconstr Surg Glob Open, 2018, 6(4): e1730.
[25]	许可可，吴旻昊，孙文超，等. 透析相关性肿瘤样钙化19例诊疗体会[J]. 临床外科杂志，2018, 26(8): 610-612.
[26]	Al-Rumaih MH, Al-Otaibi MA, Alshammari AN. Tumoral calcinosis presentation in operated developmental dysplasia of the hip: a case report and review of literature [J]. Cureus, 2020, 12(8): e9948.
[27]	Megaloikonomos PD, Mavrogenis AF, Panagopoulos GN, et al. Tumoral calcinosis of the shoulder [J]. Lancet Oncol, 2017, 18(2): e126.
[28]	王军辉，张国庆，刘玉珂，等. 骨化性肌炎的多模态影像学表现[J]. 中国中西医结合影像学杂志，2021, 19(2): 165-167, 179.
[29]	乔永明，王颖，李锐. 关节镜用于颞下颌关节滑膜软骨瘤病诊治的临床分析[J]. 华西口腔医学杂志，2021, 39(2): 209-214.
[30]	庄雪婷，陈杰云，林晓莹，等. 滑膜肉瘤CT及MRI表现[J]. 中国医学影像技术，2021, 37(3): 446-449.
[31]	Maioli ME, Delfino VDA, Guerra ACDZ, et al. Reversal of uremic tumoral calcinosis by optimization of clinical treatment of bone and mineral metabolism disorder [J]. J Bras Nefrol, 2017, 39(2): 217-219.
[32]	Malbos S, Urena-Torres P, Cohen-Solal M, et al. Sodium thiosulphate treatment of uraemic tumoral calcinosis [J]. Rheumatology (Oxford), 2014, 53(3): 547-551.
[33]	Zhang R, Li G, Yang L, et al. Multiple ectopic calcifications in subcutaneous tissues with chronic renal failure: a case report [J]. Int J Surg Case Rep, 2016, 29: 113-119.
[34]	Li J, Yan M, Ren L, et al. Intravenous sodium thiosulfate combined with parathyroidectomy as a cure for uremic tumoral calcinosis in a hemodialysis patient [J]. Joint Bone Spine, 2021, 88(1): 105043.
[35]	张蕊，徐志宏，于明安，等. 微波消融术治疗继发性甲状旁腺功能亢进症改善肿瘤样钙质沉着症1例[J]. 中国血液净化，2017, 16(5): 359-360.

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