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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2023, Vol. 12 ›› Issue (04): 220-223. doi: 10.3877/cma.j.issn.2095-3216.2023.04.008

• Review • Previous Articles     Next Articles

Progress of research on the relationship between serine protease corin and kidney disease

Yanru Zhang, Xiaole Su, Lihua Wang()   

  1. Department of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China
  • Received:2022-09-15 Online:2023-08-28 Published:2023-08-15
  • Contact: Lihua Wang

Abstract:

Corin is a serine protease widely distributed in the epithelial tissues of the kidney. It can activate atrial natriuretic peptide, having natriuretic, water excretion, and vasodilation effects. This article reviewed the progress of research on the relationship between corin and diseases such as hypertension and chronic kidney disease, in order to explore its potential as a biomarker for kidney disease.

Key words: Kidney disease, Serine protease, Atrial natriuretic peptide, Diagnosis, Treatment

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