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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2024, Vol. 13 ›› Issue (02): 97-100. doi: 10.3877/cma.j.issn.2095-3216.2024.02.007

• Review • Previous Articles    

Research progress on the efficacy and strategy of SARS-CoV-2 vaccination in patients with chronic kidney disease

Jinyi Zhang1, Yuehong Li2,()   

  1. 1. Tsinghua University School of Medicine
    2. Department of Nephrology, Beijing Tsinghua Changgeng Hospital; Beijing 102218, China
  • Received:2023-03-27 Online:2024-04-28 Published:2024-05-13
  • Contact: Yuehong Li

Abstract:

Patients with chronic kidney disease, especially end-stage renal disease, who are receiving renal replacement therapy, are at great risk in the epidemic of COVID-19. Studies have shown that the existing COVID-19 vaccines are safe for patients with chronic kidney disease, and the whole course of vaccination can produce specific antibodies in most patients with chronic kidney disease. However, the humoral response and efficacy of the vaccines in patients with chronic kidney disease were significantly weaker than in healthy people. Increase of the number of vaccinations and use of combined vaccinations may have potential value in improving the protective efficacy of the vaccines in patients with chronic kidney disease, but the relevant vaccination strategies still need to be further studied. This paper reviewed the research progress on the feasibility, safety, efficacy, and targeted vaccination strategies of the SARS-CoV-2 vaccination for patients with chronic kidney disease.

Key words: Chronic kidney disease, COVID-19, SARS-CoV-2, Vaccination

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