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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2021, Vol. 10 ›› Issue (02): 113-116. doi: 10.3877/cma.j.issn.2095-3216.2021.02.011

Special Issue:

• Review • Previous Articles     Next Articles

Adeno-associated virus and renal tubular-targeted gene transduction

Qiang Ma1, Qiangguo Ao1, Yabin Zhang1, Qingli Cheng1,()   

  1. 1. Department of Nephrology and National Institute of Geriatrics, Second Medical Center of General Hospital of Chinese PLA, Beijing 100853, China
  • Received:2020-12-21 Online:2021-04-30 Published:2021-05-24
  • Contact: Qingli Cheng

Abstract:

Renal gene therapy has been studied in recent years, and some progress has been made. The research focus was mainly on adeno-associated virus. This article summarized the research progress of adeno-associated virus in gene transduction, reviewed the different transduction pathways and gene vectors of gene transduction targeting the renal tubules, and discussed the gene transduction strategies and the existing problems in adeno-associated virus gene transduction targeting the renal tubules.

Key words: Adeno-associated virus, Renal tubule, Gene transduction

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