To investigate the impact of the time interval from coronary angiography to valvular surgery on the occurrence of postoperative acute kidney injury (AKI).

Preoperative baseline data, surgical data, and clinical prognosis data of patients, who were admitted to the First Affiliated Hospital of Nanjing Medical University from January 2017 to December 2018 and underwent both coronary angiography and cardiac valve surgery, were collected retrospectively. Propensity score matching, univariate and multivariate logistic regression methods were used to investigate the impact of the time interval from coronary angiography to valvular surgery on the occurrence of postoperative AKI.

A total of 338 patients were enrolled in the study, among whom there were 164 female patients. The incidence of postoperative AKI was 25.4% (86/338). According to the median time interval of 6 days, all the patients were divided into two groups: ≤6 d group (206 cases) and >6 d group (132 cases). There were no significant differences between the two groups in preoperative baseline indicators, intraoperative related indicators, and the incidence of AKI. Univariate regression analysis showed that age, baseline creatinine, estimated glomerular filtration rate, operation time, extracorporeal circulation time, aortic cross-clamp time, and cardiac arrest time were all the related risk factors for AKI after valve surgery, but there was no significant correlation between the 6-day interval and the occurrence of AKI after cardiac valve surgery. And the multivariate logistic regression analysis also showed that there was no significant correlation between the 6-day interval and the occurrence of postoperative AKI.

The time interval between coronary angiography and valvular surgery may not be an independent risk factor for the postoperative AKI.