A case report of acute tubular necrosis caused by non-traditional causes

doi:10.3877/cma.j.issn.2095-3216.2021.06.011

Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2021, Vol. 10 ›› Issue (06): 352-354. doi: 10.3877/cma.j.issn.2095-3216.2021.06.011

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A case report of acute tubular necrosis caused by non-traditional causes

Li Kang¹, Xiaoyue Hou¹, Kai Rong¹

Received:2021-03-05 Online:2021-12-28 Published:2022-01-05

Abstract

Li Kang, Xiaoyue Hou, Kai Rong. A case report of acute tubular necrosis caused by non-traditional causes[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2021, 10(06): 352-354.

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日期	BUN(mmol/L)	Cr(μmol/L)	UA(μmol/L)	NGAL(ng/ml)	尿蛋白	尿蛋白定量(mg/d)	尿量(ml/d)	症状及处理
2020.10.24	9.6	166.5	417.0		2+	384.0	800	腰部绞痛
2020.10.25(9：00AM)	15.4	305.8	501.0				850	腰部绞痛
2020.10.25(16：20)	17.3	326.0	499.0					腰部绞痛
2020.10.26入院							1 000	腰痛
2020.10.27	26.0	553.3	564.7	18.0	Trace		1 000	间断腰痛，彩超血管未见血栓
2020.10.28	26.8	605.2	611.5		1+		900	腰痛，行肾穿检查
2020.10.29	27.5	610.3	647.4		Trace		850	行全腹三期强化CT
2020.10.30	22.9	473.8	476.1		1+		1 170	第一次CRRT；肾病理：ATN
2020.10.31	24.2	471.7	556.8				1 050	腰痛减轻
2020.11.01	21.4	371.6	397.0				1 680	第二次CRRT
2020.11.02	22.2	362.2	456.6					腰痛减轻
2020.11.03	21.1	369.4	466.4				2 000	腰痛减轻
2020.11.04	18.9	306.2	485.9			119.4	3 500	腰痛明显减轻
2020.11.05	18.2	242.5	394.2	24.2	-		4 000	腰痛完全缓解
2020.11.07	16.4	182.6	316.2				4 000	无不适
2020.11.09	12.0	153.4	280.7				3 800	无不适
2020.11.11	11.2	130.6	270.3		-	125.4	4 100	无不适
2020.11.12	10.2	120.0	253.4				3 500	出院
2020.11.21门诊复查	7.1	101.3	286.4		-	105.1	2 800	无不适

日期	BUN(mmol/L)	Cr(μmol/L)	UA(μmol/L)	NGAL(ng/ml)	尿蛋白	尿蛋白定量(mg/d)	尿量(ml/d)	症状及处理
2020.10.24	9.6	166.5	417.0		2+	384.0	800	腰部绞痛
2020.10.25(9：00AM)	15.4	305.8	501.0				850	腰部绞痛
2020.10.25(16：20)	17.3	326.0	499.0					腰部绞痛
2020.10.26入院							1 000	腰痛
2020.10.27	26.0	553.3	564.7	18.0	Trace		1 000	间断腰痛，彩超血管未见血栓
2020.10.28	26.8	605.2	611.5		1+		900	腰痛，行肾穿检查
2020.10.29	27.5	610.3	647.4		Trace		850	行全腹三期强化CT
2020.10.30	22.9	473.8	476.1		1+		1 170	第一次CRRT；肾病理：ATN
2020.10.31	24.2	471.7	556.8				1 050	腰痛减轻
2020.11.01	21.4	371.6	397.0				1 680	第二次CRRT
2020.11.02	22.2	362.2	456.6					腰痛减轻
2020.11.03	21.1	369.4	466.4				2 000	腰痛减轻
2020.11.04	18.9	306.2	485.9			119.4	3 500	腰痛明显减轻
2020.11.05	18.2	242.5	394.2	24.2	-		4 000	腰痛完全缓解
2020.11.07	16.4	182.6	316.2				4 000	无不适
2020.11.09	12.0	153.4	280.7				3 800	无不适
2020.11.11	11.2	130.6	270.3		-	125.4	4 100	无不适
2020.11.12	10.2	120.0	253.4				3 500	出院
2020.11.21门诊复查	7.1	101.3	286.4		-	105.1	2 800	无不适

[1]	Lameire N, Van Biesen W, Vanholder R. Acute renal failure [J]. Lancet, 2005, 365(9457): 417-430.
[2]	Esson ML, Schrier RW. Diagnosis and treatment of acute tubular necrosis [J]. Ann Intern Med, 2002, 137(9): 744-752.
[3]	曾庆义，周才芳，曾秀琴. 尿NGAL在微小病变型肾病并急性肾小管坏死中的诊断价值分析. 医学理论与实践[J]. 2020, 33(6): 980-982.
[4]	李一飞，姚广涛. 急性肾损伤中肾小管损伤标志物的研究进展. 中国实验方剂学杂志[J]. 2011, 17(23): 279-283.
[5]	Ko GJ, Grigoryev DN, Linfert D, et al. Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition [J]. Am J Physiol Renal Physiol, 2010, 298(6): F1472-F1483.

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