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中华肾病研究电子杂志 ›› 2018, Vol. 07 ›› Issue (01) : 4 -7. doi: 10.3877/cma.j.issn.2095-3216.2018.01.002

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马兜铃酸肾病:仍需关注的全球性公共卫生问题
阳晓1,(), 吴娟1, 余学清1   
  1. 1. 510080 广州,中山大学附属第一医院肾内科
  • 收稿日期:2017-12-21 出版日期:2018-02-28
  • 通信作者: 阳晓
  • 基金资助:
    国家自然科学基金(81570614、81774069); 广东省自然科学基金(2014A030313139); 卫计委公益性行业科研专项(201502023)

Aristolochic acid nephropathy: a global public health issue that still needs attention

Xiao Yang1,(), Juan Wu1, Xueqing Yu1   

  1. 1. Department of Nephrology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
  • Received:2017-12-21 Published:2018-02-28
  • Corresponding author: Xiao Yang
  • About author:
    Corresponding author: Yang Xiao, Email:
引用本文:

阳晓, 吴娟, 余学清. 马兜铃酸肾病:仍需关注的全球性公共卫生问题[J]. 中华肾病研究电子杂志, 2018, 07(01): 4-7.

Xiao Yang, Juan Wu, Xueqing Yu. Aristolochic acid nephropathy: a global public health issue that still needs attention[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2018, 07(01): 4-7.

马兜铃酸肾病(AAN)不仅是我国常见的慢性肾间质性疾病,而且也是巴尔干肾病的致病因素之一。由于涉及的地域及人群广泛,且目前尚无有效治疗方案,相当比例的AAN患者肾功能进行性减退至终末期肾衰竭(ESRD),已成为全球性的公共卫生问题。加强有关AA肾毒性的宣传教育和监督管理,进一步探讨AAN的发病机制,寻找有效干预靶点,不仅对于正确认识和使用中医药,而且对于减少ESRD患病率具有重要的科学和现实意义。

Aristolochic acid nephropathy (AAN) is not only a common chronic renal interstitial disease in China, but also one of the pathogenic factors of Balkan endemic nephropathy. Due to the disease involvement of a large geographic area and population, and the lack of effective treatment, a significant proportion of AAN patients progress to end-stage renal disease (ESRD), which has become a global public health problem. Strengthening the publicity, education, supervision, and management of AA nephrotoxicity, further exploring the pathogenesis of AAN, and seeking effective intervention targets have important scientific and practical significance for not only correct understanding and use of Chinese medicine, but also reducing the prevalence of ESRD.

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