Reasonable application of antibiotics in kidney disease

doi:10.3877/cma.j.issn.2095-3216.2014.05.002

Abstract

Abstract:

The pharmacokinetics in patients with chronic kidney disease (CKD) is quite different from that in patients with normal renal function. In patients with CKD,the dose or dosing interval of antibiotics excreted by kidneys should be adjusted appropriately,otherwise the side effects of the drugs may be increased.In contrast, blood purification treatment in patients with chronic renal failure, often results in the decrease of blood concentration of antibiotics. In order to maintain the consistent efficacy of antibiotic drugs,supplemental dosing during or after hemodialysis is sometimes required for patients with end-stage renal disease (ESRD).This article will discuss specifically how to reasonably apply antibiotics in patients with kidney diseases.

Key words: Antibiotic, Kidney disease

Jingai Fang, Xiaodong Zhang. Reasonable application of antibiotics in kidney disease[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2014, 03(05): 233-235.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhsbyjdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-3216.2014.05.002

https://zhsbyjdzzz.cma-cmc.com.cn/EN/Y2014/V03/I05/233

References 10

1	Masereeuw R, Mutsaers HA, Toyohara T, et al. The kidney and uremic toxin removal: glomerulus or tubule [J] ? Semin Nephrol,2014,34(2):191-208.
2	Tong Z, Yerramilli U, Surapaneni S, et al. The interactions of lenalidomide with human uptake and efflux transporters and UDP-glucuronosyltransferase 1A1:lack of potential for drug-drug interactions[J]. Cancer Chemother Pharmacol,2014,73(4):869-874.
3	Levey AS, Inker LA, Coresh J. GFR estimation: from physiology to public health [J]. Am J Kidney Dis,2014,63(5):820-834.
4	Fissell WH. Antimicrobial dosing in acute renal replacement[J].Adv Chronic Kidney Dis,2013,20(1):85-93.
5	Bailey O,Torkington MS,Anthony I,et al. Antibiotic-related acute kidney injury in patients undergoing elective joint replacement [J].Bone Joint J,2014,96-B(3):395-398.
6	Zuber K, Liles AM, Davis J. Medication dosing in patients with chronic kidney disease [J]. JAAPA,2013,26(10):19-25.
7	Zhang A, Sun H, Qiu S, et al. Metabolomics insights into pathophysiological mechanisms of nephrology [J]. Int Urol Nephrol,2014,46(5):1025-1030.
8	Huddam B, Azak A, Kocak G, et al. The efficacy of prophylactic antibiotics administration prior to insertion of tunneled catheter in hemodialysis patients [J]. Ren Fail,2012,34(8):998-1001.
9	Wilson FP, Berns JS. Vancomycin levels are frequently subtherapeutic during continuous venovenous hemodialysis(CVVHD) [J]. Clin Nephrol,2012,77(4):329-331.
10	Fissell WH. Antimicrobial dosing in acute renal replacement [J].Adv Chronic Kidney Dis,2013,20(1):85-93.

[1]	Xiaoqing Tang, Ping He, You Yang, Xia Luo, Juying Zhang, Xin Yang, Jinhong Yu. Correlation of sound touch elastography combined with pulsed wave Doppler ultrasound imaging parameters with stage of early chronic kidney disease and their clinical significance [J]. Chinese Journal of Medical Ultrasound (Electronic Edition), 2024, 21(05): 491-499.
[2]	Zhigang Xu, Tao Cao, Ting He, Boao Li, Jingtao Wei, Dongliang Zhang, Hao Guan, Xuekang Yang. Clinical effect of antibiotic bone cement in the treatment of sternal osteomyelitis after cardiac surgery for patients with diabetes mellitus [J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2024, 19(06): 498-502.
[3]	Shan Jiang, Xiangyan Li, Shuohan Tian, Bing Wen, Rui He, Xin Qi. Clinical observation of optimized anti-infective treatment model to improve the prognosis of diabetic foot infection [J]. Chinese Journal of Injury Repair and Wound Healing(Electronic Edition), 2024, 19(05): 398-403.
[4]	Song Liu, Jinzhao Zhang, Yanyun Jia. Relationship between reduced response to pabolizumab in treatment of advanced non-small cell lung cancer and antibiotic preconditioning [J]. Chinese Journal of Lung Diseases(Electronic Edition), 2024, 17(04): 553-557.
[5]	Xuefeng Zhou, Zheyi Dong, Zhe Feng, Guangyan Cai, Xiangmei Chen. Formulation protocol of guidelines for diagnosis and treatment of diabetic kidney disease with integrated traditional Chinese and Western medicine [J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2024, 13(06): 301-305.
[6]	Bokai Cheng, Guang Yang. Progress of research on application of hyperinsulinemic-euglycemic clamp technique for assessing insulin resistance in patients with chronic kidney disease [J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2024, 13(06): 334-339.
[7]	Tao Wang, Jing Liu, Yuwei Gao, Xinghua Wang, Xiuhong Hu, Hongrui Cui, Baozhen Xu, Hongjuan Yang. Research progress in the prevention and treatment of peritoneal dialysis-associated peritonitis with traditional Chinese medicine under the background of antibiotic resistance [J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2024, 13(06): 340-344.
[8]	Rongrong Feng, Xiaole Su, Lihua Wang. Research progress on biological markers related to complication of cardiovascular disease in patients with chronic kidney disease [J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2024, 13(05): 273-278.
[9]	Junnan Guo, Hui Lin, Yilin Ren, Xi Qiao. Progress of research on the role of amino acid metabolism disturbance in the transition from AKI to CKD [J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2024, 13(05): 283-287.
[10]	Xiaolong Wang, Jie Wu, Shuwei Duan, Chaohui Wang, Na Pan, Yuanyuan Bai, Hangtian Li, Guangyan Cai. Effect of different levels of physical activity on the prognosis of patients with chronic kidney disease [J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2024, 13(03): 121-128.
[11]	Wenqi Lu, Yanru Zhao, Huandi Li, Xinna Fan, Jia Wang, Ping Li. Serum expression of SMAD2 and SOX6 in patients with type 2 diabetes mellitus and their relationship with proteinuria [J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2024, 13(03): 145-151.
[12]	Force on Experts Consensus on Extended Infusion of β-Lactam Task. Experts consensus on extended infusion of β-lactam antibiotics in adult sepsis patients [J]. Chinese Journal of Critical Care & Intensive Care Medicine(Electronic Edition), 2024, 10(04): 313-324.
[13]	Peipei Xi, Jiajun Zhou. Progress in research of sarcopenia in patients with chronic kidney disease: pathogenesis, diagnosis, and treatment [J]. Chinese Journal of Clinicians(Electronic Edition), 2024, 18(05): 491-495.
[14]	Lei Zhu, Qingyi Zhu. Kingella: An emerging pathogen of invasive infections disease in young children [J]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2024, 12(04): 229-237.
[15]	Mei Zhang, Hui Chen, Zhuanxia Li, Rui Wang, Linjuan Li. Metrnl and NLRP3 Inflammasome: Potential diagnostic biomarkers for diabetic kidney disease [J]. Chinese Journal of Obesity and Metabolic Diseases(Electronic Edition), 2024, 10(03): 193-199.

Please choose a citation manager

Content to export