Metabolism-related diseases which can cause renal damage, refer to diabetes, hypertension, obesity, lipid metabolism disorders, hyperuricemia, sleep apnea, and so on. It′s pathogenesis is associated with poor control of primary diseases, insulin resistance, chronic inflammatory status, and endothelial dysfunction, etc. Healthy lifestyle, strict weight management, control of blood glucose and blood pressure, treatment of blood lipids and hyperuricemia, and correction of sleep apnea are the key for prevention and treatment of renal damage in metabolism-related diseases.