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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2021, Vol. 10 ›› Issue (01): 44-46. doi: 10.3877/cma.j.issn.2095-3216.2021.01.009

Special Issue:

• Review • Previous Articles     Next Articles

Research progress of fatty acid-binding protein 4 in kidney diseases

Xiaoyan Du1, Rongshuang Huang2, Liang Ma3,(), Ping Fu2   

  1. 1. Department of Pharmacy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
    2. Department of Nephrology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
    3. Department of Pharmacy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China; Department of Nephrology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
  • Received:2020-10-06 Online:2021-02-28 Published:2021-02-28
  • Contact: Liang Ma

Abstract:

Fatty acid-binding protein 4 (FABP4) plays an important regulatory role in the body′s energy metabolism and inflammatory response, and is closely related to diabetes, obesity, atherosclerosis, and tumors. Considerable studies have confirmed that FABP4 is involved in the pathophysiological process of a variety of kidney diseases, and is expected to become a potential drug target as well as a biomarker for the diagnosis of kidney diseases. This article reviewed the research progress of FABP4 in renal diseases in recent years, combining the research work of the authors′ group.

Key words: Fatty acid-binding protein 4, Kidney disease, Biomarker

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