Abstract:

Renal failure is a serious disease threatening human health, which brings heavy burden to the patients′ families and society. Clinical studies and experience tell us that although patients with end-stage renal disease can benefit from maintenance hemodialysis, a lot of studies have found that cardiovascular complications of hemodialysis are the main cause of death. Early monitoring the occurrence of cardiovascular complications in hemodialysis patients, carrying out targeted and reasonable treatment in advance, and thus prolonging the life of patients, have become a problem that clinicians and scholars must think about. A large number of studies suggest that the micro-inflammatory state in patients with renal failure is closely related to cardiovascular complications. By monitoring the microinflammation-related cells and factors in patients, people can predict the prognosis of cardiovascular complications in maintenance hemodialysis patients and monitor the disease progression of hemodialysis patients. In recent years, some emerging inflammatory monitoring indicators, such as neutrophil to lymphocyte ratio, monocyte to lymphocyte ratio, and monocyte to high density lipoprotein cholesterol ratio, play a unique and positive role in predicting cardiovascular complications in patients with continuous hemodialysis, compared with the currently-used clinical inflammatory indicators such as C-reactive protein. In this article, the role of microinflammatory factors, especially the new inflammatory indicators mentioned above, in monitoring cardiovascular complications of hemodialysis patients was reviewed.

Key words: Microinflammation, Renal failure, Hemodialysis, Cardiovascular disease