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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2022, Vol. 11 ›› Issue (06): 307-310. doi: 10.3877/cma.j.issn.2095-3216.2022.06.002

• Original Article • Previous Articles     Next Articles

Evaluation of carotid atherosclerosis and its influencing factors in patients with chronic renal failure

Min Xu1,(), Shifeng Lai1, Na Luo1, Huimin Li1   

  1. 1. Jianyang People′s Hospital, Jianyang 641400, Sichuan Province, China
  • Received:2021-10-26 Online:2022-12-28 Published:2023-01-17
  • Contact: Min Xu

Abstract:

Objective

To evaluate carotid atherosclerosis in patients with chronic renal failure and analyze its influencing factors.

Methods

The clinical data of 148 patients with chronic renal failure were analyzed retrospectively. The incidence of carotid atherosclerosis under high-frequency color Doppler ultrasound was calculated, and the influencing factors were analyzed by logistic regression.

Results

There were 97 cases of carotid atherosclerosis with an incidence of 65.54%. There was no statistically significant difference between the sclerotic group and the non-sclerotic group in gender and dialysis method (P>0.05). The sclerotic group was significantly higher than the non-sclerotic group in the following indicators (P<0.05), including age>60 years, body mass index (BMI)>25 kg/m2, general nutrition assessment (GNA)≥7.5 points, smoking package ≥5 years, diabetes, hypertension, hyperlipidemia, hyperuricemia course of renal failure ≥3 years, dialysis time > 1 year. Logistic regression analysis showed that the following indicators were influencing factors of carotid atherosclerosis in patients with renal failure, including age>60 years, body mass index (BMI)>25 kg/m2, global nutrition assessment (GNA)≥7.5 points, smoking package ≥5 years, diabetes, hypertension, hyperlipidemia, hyperuricemia course of renal failure≥ 3 years, and dialysis time >1 year.

Conclusion

The prevalence of carotid atherosclerosis in patients with chronic renal failure was 65.54%. The factors including age>60 years, BMI>25 kg/m2, GNA ≥7.5 points, smoking package years ≥5 years, diabetes, hypertension, hyperlipidemia, hyperuricemia, renal failure course ≥3 years, and dialysis time>1 year were closely related to the higher prevalence of carotid atherosclerosis in patients with chronic renal failure.

Key words: Chronic renal failure, Carotid atherosclerosis, Influencing factors, High frequency color ultrasound

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