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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2022, Vol. 11 ›› Issue (06): 301-306. doi: 10.3877/cma.j.issn.2095-3216.2022.06.001

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RAAS inhibitors in the treatment of patients with chronic kidney disease accompanied by heart failure

Xuefeng Sun1,()   

  1. 1. Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Beijing 100853, China
  • Received:2022-06-21 Online:2022-12-28 Published:2023-01-17
  • Contact: Xuefeng Sun

Abstract:

Renin angiotensin aldosterone system (RAAS) inhibitors are the basic drugs for the treatment of chronic kidney disease and heart failure, but there are still problems in the application of RAAS inhibitors for patients with chronic kidney disease accompanied by heart failure. Based on evidence-based medicine, this paper introduced the pharmacological effects of different kinds of RAAS inhibitors, and discussed the efficacy of RAAS inhibitors in the treatment of chronic kidney disease and heart failure, as well as problems in the combined application of RAAS inhibitors, so as to provide reference for clinicians to reasonably use RAAS inhibitors in the treatment of patients with chronic kidney disease accompanied by heart failure.

Key words: RAAS inhibitor, Chronic kidney disease, Heart failure

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