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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2014, Vol. 03 ›› Issue (06): 289-293. doi: 10.3877/cma.j.issn.2095-3216.2014.06.002

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Evidence-based medicine in the treatment of hypertension

Zhaohui Ni1,(), Qi Zhang1   

  1. 1.Department of Nephrology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China
  • Online:2014-12-15 Published:2024-11-28
  • Contact: Zhaohui Ni

Abstract:

Hypertension greatly affects the health of human beings in the world. It interacts with chronic kidney disease (CKD) in many different ways. CKD patients have a high morbidity of hypertension whose control rate is low, with high risk of cardiovascular disease (CVD) and death. Many guidelines and studies have shown that rational treatment of hypertension can slow down the progression of kidney diseases,prevent the damage of organs, decrease the morbidity of clinical diseases, and decrease the mortality of CVD in CKD patients. At present, it is recommended to use renin-angiotensin system (RAS) inhibitors, calcium channel blockers (CCBs), or combined therapy to achieve optimal blood pressure. There is no clinical practice guideline for management of CKD hypertension in China because of the deficiency of intervention information. The evidence-based medicine of hypertension in Chinese CKD patients is urgently needed.

Key words: Hypertension, Chronic kidney disease, Cardiovascular disease, Evidence-based medicine

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