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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2016, Vol. 05 ›› Issue (04): 155-158. doi: 10.3877/cma.j.issn.2095-3216.2016.04.003

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Progress of research on application of oral antidiabetic agents for patients with diabetic nephropathy

Niansong Wang1,(), Li He1, Dongsheng Cheng1,()   

  1. 1. Department of Nephrology, Sixth People′s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200233, China

Abstract:

Diabetic nephropathy (DN) is one of the most common causes for end-stage renal disease (ESRD) in the world. Intensive glucose control is effective in decreasing the incidence and progression of DN. As the renal function reduces, accumulation of hypoglycemic drugs can occur in the patients, which increases adverse reactions of the drugs as well as hypoglycemia events. This article mainly discussed the application of oral hypoglycemic drugs used for DN, including insulin secretagogues, non-insulin secretagogues, and other new type of oral hypoglycemic drugs.

Key words: Diabetic nephropathy, Insulin secretagogues, Non-insulin secretagogues, Oral hypoglycemic drugs, new type

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