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Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2020, Vol. 09 ›› Issue (05): 232-235. doi: 10.3877/cma.j.issn.2095-3216.2020.05.009

Special Issue:

• Review • Previous Articles     Next Articles

Application of proteomics and metabolomics in the study of diabetic kidney disease

Xiaonan Ding1, Qiuxia Han2, Dong Zhang2, Hanyu Zhu2,()   

  1. 1. Medical School of Chinses PLA, Beijing 100853, China; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Beijing 100853, China
    2. Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Beijing 100853, China
  • Received:2020-04-15 Online:2020-10-28 Published:2020-10-28
  • Contact: Hanyu Zhu
  • About author:
    Corresponding author: Zhu Hanyu, Email:

Abstract:

Diabetic kidney disease is one of the most important causes of end-stage renal disease, and has become a major problem in public health in the world. It is a priority to resolve disputes in clinical diagnosis and treatment of the disease. This article reviewed the research progress in the diagnosis and differential diagnosis, disease progression, prognosis judgment, and efficacy evaluation of diabetic kidney disease, by means of proteomics and metabolomics. Besides, it also explained the similarities and differences between the two omics technologies, and prospected the use of proteomics and metabolomics for research of integrated omics and precision medicine in the context of contemporary big data and artificial intelligence.

Key words: Proteomics, Metabolomics, Diabetic kidney disease

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