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中华肾病研究电子杂志 ›› 2019, Vol. 08 ›› Issue (01) : 38 -40. doi: 10.3877/cma.j.issn.2095-3216.2019.01.008

所属专题: 文献

综述

蜂蛰伤导致急性肾损伤的防治
张彬1, 何娅妮1,()   
  1. 1. 400042 重庆,陆军特色医学中心肾内科
  • 收稿日期:2018-07-01 出版日期:2019-02-28
  • 通信作者: 何娅妮

Prevention and treatment of acute kidney injury caused by bee stings

Bin Zhang1, Yani He1,()   

  1. 1. Nephrology Department, Army Specialty Medical Center, Chongqing 400042, China
  • Received:2018-07-01 Published:2019-02-28
  • Corresponding author: Yani He
  • About author:
    Corresponding author: He Yani, Email:
引用本文:

张彬, 何娅妮. 蜂蛰伤导致急性肾损伤的防治[J]. 中华肾病研究电子杂志, 2019, 08(01): 38-40.

Bin Zhang, Yani He. Prevention and treatment of acute kidney injury caused by bee stings[J]. Chinese Journal of Kidney Disease Investigation(Electronic Edition), 2019, 08(01): 38-40.

在我国、南亚及东南亚地区,蜂蛰伤事件时常发生,已经成为一个严重威胁广大民众生命和健康的问题。蜂蛰伤导致的急性肾损伤(AKI)是非常常见的严重并发症,病情凶险,危及患者生命。急性肾小管坏死(ATN)是其主要肾脏病理改变。目前认为低血压引起的缺血性肾损伤、血管内溶血、横纹肌溶解和蜂毒直接毒性作用是蜂蛰伤致AKI的主要机制。血液净化治疗是目前救治蜂蛰伤后AKI的有效方法,同时蜂毒的免疫治疗主要针对蜂毒过敏人群。本文就蜂蛰伤导致的AKI防治研究的最新进展作一综述。

In China, South Asia, and Southeast Asia, bee stings often occur and have become a serious threat to the lives and health of the vast numbers of civilians. Acute kidney injury (AKI) caused by bee stings is a very common serious complication, and the condition is dangerous and can endanger the life of the patient, with acute tubular necrosis (ATN) being the major renal pathological change. It is currently believed that the main mechanisms of AKI caused by bee stings includes hypotension-induced ischemic renal injury, intravascular hemolysis, rhabdomyolysis, and direct renal toxicity of bee venom components. Blood purification therapy is an effective method to treat AKI caused by bee stings, and the venom-specific immunotherapy is mainly aimed at the allergic population. This paper reviewed the recent advances in the research on prevention and treatment of AKI caused by bee stings.

[1]
Xie C,Xu S,Ding F, et al. Clinical features of severe wasp sting patients with dominantly toxic reaction: analysis of 1091 cases [J]. PLoS One, 2013, 8(12): e83164.
[2]
Vikrant S,Parashar A. Acute kidney injury due to multiple hymenoptera stings-a clinicopathological study [J]. Clin Kidney J, 2017, 10(4): 532-538.
[3]
Xuan BH,Mai HL,Thi TX, et al. Swarming hornet attacks: shock and acute kidney injury-a large case series from Vietnam [J]. Nephrol Dial Transplant, 2010, 25(4): 1146-1150.
[4]
Zhang L,Yang Y,Tang Y, et al. Recovery from AKI following multiple wasp stings: a case series [J]. Clin J Am Soc Nephrol, 2013, 8(11): 1850-1856.
[5]
Myatt EA,Stevens FJ,Benjamin C. Solution-phase binding of monoclonal antibodies to bee venom phospholipase A2 [J]. J Immunol Methods, 1994, 177(1-2): 35-42.
[6]
Terra RM,Guimaraes JA,Verli H. Structural and functional behavior of biologically active monomeric melittin [J]. J Mol Graph Model, 2007, 25(26): 767-772.
[7]
Silva GBD Junior,Vasconcelos AG Junior,Rocha AMT, et al. Acute kidney injury complicating bee stings- a review [J]. Rev Inst Med Trop Sao Paulo, 2017, 59: e25.
[8]
Oliveira EC,Pedroso PM,Meirelles AE, et al. Pathological findings in dogs after multiple Africanized bee stings [J]. Toxicon, 2007, 49(8): 1214-1218.
[9]
Grisotto LS,Mendes GE,Castro I, et al. Mechanisms of bee venom-induced acute renal failure [J]. Toxicon, 2006, 48(1): 44-54.
[10]
Arruda VM,Alves VV Jr,Moraes MM, et al. Morphologic analysis of the venom gland of Apis mellifera L. (Hymenoptera: Apidae) in populations of Mato Grosso do Sul, Brazil [J]. Neotrop Entomol, 2007, 36(2): 203-209.
[11]
França FO,Benvenuti LA,Fan HW, et al. Severe and fatal mass attacks by killer bees (Africanized honey bees - Apis mellifera scutellata) in Brazil: clinicopathological studies with measurement of serum venom concentrations [J]. Q J Med, 1994, 87(5): 269-282.
[12]
Chao YW,Yang AH,Ng YY, et al. Acute interstitial nephritis and pigmented tubulopathy in a patient after wasp stings [J]. Am J Kidney Dis, 2004, 43(2): e15-e19.
[13]
Mingomataj EC,Bakiri AH,Ibranji A, et al. Unusual reactions to hymenoptera stings: what should we keep in mind? [J]. Clin Rev Allergy Immunol, 2014, 47(1): 91-99.
[14]
Nandi M,Sarkar S. Acute kidney injury following multiple wasp stings [J]. Pediatr Nephrol, 2012, 27(12): 2315-2317.
[15]
Hommel D,Bollandard F,Hulin A. Multiple African honeybee stings and acute renal failure [J]. Nephron, 1998, 78(2): 235-236.
[16]
Muñoz-Arizpe R,Velásquez-Jones L,Roremo-Navarro B, et al. Acute kidney failure due to stings by Africanized bees [J]. Bol Med Hosp Infant Mex, 1992, 49(6): 388-390.
[17]
Bridi RA,Balbi AL,Neves PM, et al. Acute kidney injury after massive attack of Africanised bees [J]. BMJ Case Rep, 2014, pii: bcr2013201381.
[18]
Vanholder R,Sever MS,Erek E, et al. Rhabdomyolysis [J]. J Am Soc Nephrol, 2000, 11(8): 1553-1561.
[19]
Zager RA. Rhabdomyolysis and myohemoglobinuric acute renal failure [J]. Kidney Int, 1996, 49(2): 314-326.
[20]
Reis MA,Costa RS,Coimbra TM, et al. Acute renal failure in experimental envenomation with Africanized bee venom [J]. Ren Fail, 1998, 20(1): 39-51.
[21]
Reis MA,Costa RS,Coimbra TM, et al. Renal changes induced by envenomation with Africanized bee venom in female Wistar rats [J]. Kidney Blood Press Res, 1997, 20(4): 271-277.
[22]
Daher EF,Oliveira RA,Silva LS, et al. Acute renal failure following bee stings: case reports [J]. Rev Soc Bras Med Trop, 2009, 42(2): 209-212.
[23]
Ceri M,Kurultak I. Relapse of nephrotic syndrome after a bee sting [J]. Indian J Nephrol, 2012, 22(2): 151-152.
[24]
Muraro A,Roberts G,Worm M, et al. Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology [J]. Allergy, 2014, 69(8): 1026-1045.
[25]
Xuan BH,Mai HL,Thi TX, et al. Swarming hornet attacks: shock and acute kidney injury-a large case series from Vietnam [J]. Nephrol Dial Transplant, 2010, 25(4): 1146-1150.
[26]
Paudel B,Paudel K. A study of wasp bites in a tertiary hospital of western Nepal [J]. Nepal Med Coll J, 2009, 11(1): 52-56.
[27]
Bresolin NL,Carvalho LC,Goes EC, et al. Acute renal failure following massive attack by Africanized bee stings [J]. Pediatr Nephrol, 2002, 17(8): 625-627.
[28]
Dhanapriya J,Dineshkumar T,Sakthirajan R, et al. Wasp sting-induced acute kidney injury [J]. Clin Kidney J, 2016, 9(2): 201-204.
[29]
Dhanapriya J,Dineshkumar T,Sakthirajan R, et al. Wasp sting-induced acute kidney injury [J]. Clin Kidney J, 2016, 9(2): 201-204.
[30]
Si X,Li J,Bi X et al. Clinical evaluation of high-volume hemofiltration with hemoperfusion followed by intermittent haemodialysis in the treatment of acute wasp stings complicated by multiple organ dysfunction syndrome [J]. PLoS One, 2015, 10(7): e0132708.
[31]
Golden DB,Demain J,Freeman T, et al. Stinging insect hypersensitivity: a practice parameter update 2016 [J]. Ann Allergy Asthma Immunol, 2017, 118(1): 28-54.
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