Home    中文  
 
  • Search
  • lucene Search
  • Citation
  • Fig/Tab
  • Adv Search
Just Accepted  |  Current Issue  |  Archive  |  Featured Articles  |  Most Read  |  Most Download  |  Most Cited

Chinese Journal of Kidney Disease Investigation(Electronic Edition) ›› 2020, Vol. 09 ›› Issue (05): 224-227. doi: 10.3877/cma.j.issn.2095-3216.2020.05.007

Special Issue:

• Review • Previous Articles     Next Articles

Progress of the application of new biological agents in treatment of kidney diseases

Caidie Xie1, Huijuan Mao1,()   

  1. 1. Department of Nephrology, Jiangsu Provincial People′s Hospital, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
  • Received:2020-06-16 Online:2020-10-28 Published:2020-10-28
  • Contact: Huijuan Mao
  • About author:
    Corresponding author: Mao Huijuan, Email:

Abstract:

For decades, standard regimens based on corticosteroids and classic immunosuppressive agents have become the main therapy for patients with immune-mediated glomerular diseases, but some patients had poor efficacy or intolerance to these classic drugs. The emergence of new biological agents has brought dawn to the targeted treatment of such diseases, and is of great significance in improving patients′ clinical symptoms and quality of life. However, the treatment options, the effectiveness, and safety of the treatment have yet to be further refined by large randomized controlled trials. This article reviewed the application progress of the widely used new biological agents like rituximab, belimumab, eculizumab, and bortezomib in the treatment of kidney diseases.

Key words: Biological agents, Rituximab, Belimumab, Eculizumab, Bortezomib

京ICP 备07035254号-35
Copyright © Chinese Journal of Kidney Disease Investigation(Electronic Edition), All Rights Reserved.
Tel: 010-66937011 E-mail: zhsbyj@126.com
Powered by Beijing Magtech Co. Ltd